Cloned (Comment) | Organism |
---|---|
expression of wild-type and mutant enzymes | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
additional information | a yqhD knockout mutant does not confer resistance to potassium tellurite and other ROS elicitors | Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.67 | - |
butanaldehyde | pH 7.0, 37°C | Escherichia coli | |
1.78 | - |
malondialdehyde | pH 7.0, 37°C | Escherichia coli | |
3.31 | - |
propionaldehyde | pH 7.0, 37°C | Escherichia coli | |
4.81 | - |
acrolein | pH 7.0, 37°C | Escherichia coli | |
28.47 | - |
acetaldehyde | pH 7.0, 37°C | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Escherichia coli | YqhD mediates resistance to potassium tellurite and other reactive oxygen species elicitors in Escherichia coli, and protects from protein oxidation, YqhD lowers toxic acrolein concentrations, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
gene yphD | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetaldehyde + NADPH + H+ | - |
Escherichia coli | ethanol + NADP+ | - |
r | |
acrolein + NADPH | - |
Escherichia coli | propenol + NADP+ | - |
r | |
butanaldehyde + NADPH | - |
Escherichia coli | butanol + NADP+ | - |
r | |
malondialdehyde + NADPH | - |
Escherichia coli | ? | - |
r | |
additional information | YqhD mediates resistance to potassium tellurite and other reactive oxygen species elicitors in Escherichia coli, and protects from protein oxidation, YqhD lowers toxic acrolein concentrations, overview | Escherichia coli | ? | - |
? | |
additional information | YqhD does not show any detectable enzymatic activity when tested with short-chain alcohols as substrates, e.g. on methanol, ethanol, propanol, butanol, or isopropanol | Escherichia coli | ? | - |
? | |
propanaldehyde + NADPH | - |
Escherichia coli | propanol + NADP+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
NADPH-dependent aldehyde reductase | - |
Escherichia coli |
YqhD | - |
Escherichia coli |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Escherichia coli |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
45.1 | - |
propionaldehyde | pH 7.0, 37°C | Escherichia coli | |
53.5 | - |
acetaldehyde | pH 7.0, 37°C | Escherichia coli | |
59.5 | - |
butanaldehyde | pH 7.0, 37°C | Escherichia coli | |
60.1 | - |
malondialdehyde | pH 7.0, 37°C | Escherichia coli | |
62.5 | - |
acrolein | pH 7.0, 37°C | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | dependent on | Escherichia coli |