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Literature summary for 1.1.1.195 extracted from

  • Bhuiyan, N.H.; Selvaraj, G.; Wei, Y.; King, J.
    Gene expression profiling and silencing reveal that monolignol biosynthesis plays a critical role in penetration defence in wheat against powdery mildew invasion (2009), J. Exp. Bot., 60, 509-521.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information CAD transcripts are accumulated in response to infection with Blumeria graminis f. sp. tritici. Accumulates at 6 hpi, followed by a slight decrease at 12 hpi and then a sharp increase at 24 hpi Triticum monococcum

Cloned(Commentary)

Cloned (Comment) Organism
from an expression sequence tag (EST) library, amplified fragments ligated into TOPO cloning vector. EST fragments in an entry vector cloned into the RNAi destination vector pIPKTA30N Triticum monococcum

Inhibitors

Inhibitors Comment Organism Structure
RNAi RNAi-mediated transient gene silencing in the epidermis leads to a higher penetration efficiency of Blumeria graminis f. sp. tritici (64%) than in the controls. Gene silencing also compromises penetration resistance to varying degrees with different genes against an inappropriate pathogen, Blumeria graminis f. sp. hordei. Co-silencing of CAD and other genes involved in monolignol biosynthesis leads to greater penetration of Blumeria graminis f. sp. tritici or Blumeria graminis f. sp. hordei than when the genes are silenced separately. Gene silencing hamperes host autofluorescence response at fungal contact sites Triticum monococcum

Organism

Organism UniProt Comment Textmining
Triticum monococcum
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Source Tissue

Source Tissue Comment Organism Textmining
epidermis CAD is accumulated in the epidermis, CAD gene expression after pathogen attack is predominantly in the epidermis Triticum monococcum
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information CAD is one of the enzymes involved in monolignol biosynthesis, which is critically important for host defence against both appropriate and inappropriate pathogen invasion in wheat Triticum monococcum ?
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Synonyms

Synonyms Comment Organism
CAD
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Triticum monococcum
cinnamyl alcohol dehydrogenase
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Triticum monococcum