Inhibitors | Comment | Organism | Structure |
---|---|---|---|
barbiturates | - |
Bos taurus | |
Diphenylhydantoin | - |
Bos taurus | |
N-ethylmaleimide | no exact differentiation between organisms in the reference | Bos taurus | |
N-ethylmaleimide | no exact differentiation between organisms in the reference | Rattus norvegicus | |
p-chloromercuribenzoate | no exact differentiation between organisms in the reference | Bos taurus | |
p-chloromercuribenzoate | no exact differentiation between organisms in the reference | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0543 | - |
D-glucuronate | no exact differentiation between organisms in the reference | Rattus norvegicus | |
0.0543 | - |
D-glucuronate | no exact differentiation between organisms in the reference | Bos taurus | |
0.0543 | - |
D-glucuronate | defined as D-glucuronate reductase | Rattus norvegicus | |
0.0543 | - |
D-glucuronate | defined as D-glucuronate reductase | Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
36000 | - |
2 * 36000, SDS-PAGE, no exact differentiation between organisms in the reference | Rattus norvegicus |
36000 | - |
2 * 36000, SDS-PAGE, no exact differentiation between organisms in the reference | Bos taurus |
60000 | 70000 | no exact differentiation between organisms in the reference, gel filtration | Rattus norvegicus |
60000 | 70000 | no exact differentiation between organisms in the reference, gel filtration | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucuronate + NADPH | Homo sapiens | - |
L-gulonate + NADP+ | - |
r | |
D-glucuronate + NADPH | Rattus norvegicus | - |
L-gulonate + NADP+ | - |
r | |
D-glucuronate + NADPH | Bos taurus | - |
L-gulonate + NADP+ | - |
r | |
L-gulonate + NADP+ | Homo sapiens | - |
D-glucuronate + NADPH | - |
r | |
L-gulonate + NADP+ | Rattus norvegicus | - |
D-glucuronate + NADPH | - |
r | |
L-gulonate + NADP+ | Bos taurus | - |
D-glucuronate + NADPH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
no exact differentiation between organisms in the reference | Rattus norvegicus |
no exact differentiation between organisms in the reference | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lens | - |
Homo sapiens | - |
lens | - |
Rattus norvegicus | - |
lens | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0025 | - |
substrate D-glucuronate, defined as D-glucuronate reductase | Rattus norvegicus |
0.0025 | - |
substrate D-glucuronate, defined as D-glucuronate reductase | Bos taurus |
0.0025 | - |
no exact differentiation between organisms in the reference | Rattus norvegicus |
0.0025 | - |
no exact differentiation between organisms in the reference | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucuronate + NADPH | - |
Homo sapiens | L-gulonate + NADP+ | - |
r | |
D-glucuronate + NADPH | - |
Rattus norvegicus | L-gulonate + NADP+ | - |
r | |
D-glucuronate + NADPH | - |
Bos taurus | L-gulonate + NADP+ | - |
r | |
L-gulonate + NADP+ | - |
Homo sapiens | D-glucuronate + NADPH | - |
r | |
L-gulonate + NADP+ | - |
Rattus norvegicus | D-glucuronate + NADPH | - |
r | |
L-gulonate + NADP+ | - |
Bos taurus | D-glucuronate + NADPH | - |
r |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 36000, SDS-PAGE, no exact differentiation between organisms in the reference | Rattus norvegicus |
dimer | 2 * 36000, SDS-PAGE, no exact differentiation between organisms in the reference | Bos taurus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
38 | - |
no exact differentiation between organisms in the reference | Rattus norvegicus |
38 | - |
no exact differentiation between organisms in the reference | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
no exact differentiation between organisms in the reference | Rattus norvegicus |
7.5 | - |
no exact differentiation between organisms in the reference | Bos taurus |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
8 | - |
no exact differentiation between organisms in the reference | Rattus norvegicus |
8 | - |
no exact differentiation between organisms in the reference | Bos taurus |
8 | - |
rapid decrease of activity above pH 8.0 | Rattus norvegicus |
8 | - |
rapid decrease of activity above pH 8.0 | Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Homo sapiens | |
NADP+ | - |
Rattus norvegicus | |
NADP+ | - |
Bos taurus | |
NADPH | - |
Homo sapiens | |
NADPH | - |
Rattus norvegicus | |
NADPH | - |
Bos taurus |