Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
progesterone + NAD(P)+ | Bos taurus | - |
20alpha-hydroxyprogesterone + NAD(P)H + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Bos taurus | D0VDT4 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
corpus luteum | - |
Bos taurus | - |
cytotrophoblast | placental cytotrophoblast villus | Bos taurus | - |
glandular epithelium | - |
Bos taurus | - |
glandular epithelium | endometrial glandular epithelial cell | Bos taurus | - |
large luteal cell | - |
Bos taurus | - |
ovary | - |
Bos taurus | - |
placenta | - |
Bos taurus | - |
placental cytotrophoblast villus | - |
Bos taurus | - |
uterine endometrium | - |
Bos taurus | - |
villus | placental cytotrophoblast villus | Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
progesterone + NAD(P)+ | - |
Bos taurus | 20alpha-hydroxyprogesterone + NAD(P)H + H+ | - |
? | |
progesterone + NADH + H+ | - |
Bos taurus | 20alpha-hydroxyprogesterone + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
20alpha-HSD | - |
Bos taurus |
20alpha-hydroxysteroid dehydrogenase | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Bos taurus |
Organism | Comment | Expression |
---|---|---|
Bos taurus | the amount of enzyme mRNA in cultured luteal cells increases with time and by treatment with the luteolysis agent prostaglandin F2alpha | up |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme regulates mechanisms involved in the maintenance of early pregnancy | Bos taurus |