Inhibitors | Comment | Organism | Structure |
---|---|---|---|
16alpha-Bromoacetoxyprogesterone | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.2 | - |
progesterone | - |
Homo sapiens | |
2.5 | - |
20alpha-hydroxyprogesterone | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
35000 | - |
1 * 35000, SDS-PAGE | Homo sapiens |
35000 | - |
2 * 35000, SDS disc gel electrophorese | Homo sapiens |
68000 | - |
- |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
co-purification with 17beta-estradiol dehydrogenase, EC 1.1.1.62, affinity chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.038 | 0.046 | calculated from 17beta-estadiol dehydrogenase activity | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
progesterone + NAD(P)H | - |
Homo sapiens | 20alpha-hydroxyprogesterone + NAD(P)+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 35000, SDS disc gel electrophorese | Homo sapiens |
monomer | 1 * 35000, SDS-PAGE | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Homo sapiens | |
NADPH | - |
Homo sapiens |