Inhibitors | Comment | Organism | Structure |
---|---|---|---|
resveratrol | non-competitive inhibitor | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | Rattus norvegicus | - |
cortisol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
3T3-L1 cell | - |
Rattus norvegicus | - |
adipocyte | - |
Rattus norvegicus | - |
adipose tissue | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
11-dehydrocorticosterone + NADPH + H+ | - |
Rattus norvegicus | ? | - |
? | |
corticosterone + NADPH + H+ | - |
Rattus norvegicus | ? | - |
? | |
cortisone + NADPH + H+ | - |
Rattus norvegicus | cortisol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
11beta-HSD1 | - |
Rattus norvegicus |
11beta-HSD2 | - |
Rattus norvegicus |
11beta-hydroxysteroid dehydrogenase type 1 | - |
Rattus norvegicus |
11beta-hydroxysteroid dehydrogenase type 2 | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0396 | - |
resveratrol | at pH 7.4 and 37°C | Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0352 | - |
at pH 7.4 and 37°C | Rattus norvegicus | resveratrol |