Cloned (Comment) | Organism |
---|---|
expressed in HEK-293 cell | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
flavone | - |
Homo sapiens | |
quercetin | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P28845 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | - |
Homo sapiens | cortisol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
11-beta-hydroxysteroid dehydrogenase type1 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
additional information | - |
16% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, 37°C | Homo sapiens | flavone | |
additional information | - |
27% inhibition at 0.01 mM, cell-based assay, pH not specified in the publication, 37°C | Homo sapiens | quercetin |