Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.146 extracted from

  • Sloboda, D.M.; Moss, T.J.; Li, S.; Matthews, S.G.; Challis, J.R.; Newnham, J.P.
    Expression of glucocorticoid receptor, mineralocorticoid receptor, and 11beta-hydroxysteroid dehydrogenase 1 and 2 in the fetal and postnatal ovine hippocampus: ontogeny and effects of prenatal glucocorticoid exposure (2008), J. Endocrinol., 197, 213-220.
    View publication on PubMed

Application

Application Comment Organism
medicine exposure of fetus to high levels of synthetic glucocorticoid may have long-lasting effects on the hippocampal expression of hypothalamic-pituitary-adrenal-related genes into adulthood Ovis aries

Organism

Organism UniProt Comment Textmining
Ovis aries
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus of animals that received betamethasone as a fetus, or whose mothers received betamethasone during pregnancy. Adult animals demonstrate increased mineralocorticoid and 11beta-HSD2 mRNA levels Ovis aries
-

Synonyms

Synonyms Comment Organism
11beta-HSD1
-
Ovis aries
11beta-hydroxysteroid dehydrogenase 1
-
Ovis aries