Literature summary for 1.1.1.146 extracted from

Zbankova, S.; Bryndova, J.; Kment, M.; Pacha, J.
Expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 in colorectal cancer (2004), Cancer Lett., 210, 95-100.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
cortisone + NADPH + H+	Homo sapiens	11betaHSD1 acts as a reductase in vivo	cortisol + NADP+	-	r

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
adenocarcinoma cell	rectum, sigmoid colon	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
cortisone + NADPH + H+	11betaHSD1 acts as a reductase in vivo	Homo sapiens	cortisol + NADP+	-	r

Synonyms

Synonyms	Comment	Organism
11beta-hydroxysteroid dehydrogenase type 1	-	Homo sapiens
11betaHSD1	-	Homo sapiens

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Release 2023.1 (January 2023)