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Literature summary for 1.1.1.145 extracted from

  • Nicolau-Solano, S.I.; McGivan, J.D.; Whittington, F.M.; Nieuwhof, G.J.; Wood, J.D.; Doran, O.
    Relationship between the expression of hepatic but not testicular 3beta-hydroxysteroid dehydrogenase with androstenone deposition in pig adipose tissue (2006), J. Anim. Sci., 84, 2809-2817.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, tissue-specific expression analysis Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
trilostane specific enzyme inhibitor Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Sus scrofa
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
androstenone + NADH Sus scrofa
-
beta-androstenol + NAD+
-
?
additional information Sus scrofa relationship between the expression of hepatic but not testicular enzyme with androstenone deposition in pig adipose tissue, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa Q9N119 bifunctional enzyme that also catalyzes the reaction of the steroid DELTA5-DELTA4 isomerase, EC 5.3.3.1; large White and Meishan pigs, bifunctional enzyme
-

Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue
-
Sus scrofa
-
liver
-
Sus scrofa
-
additional information relationship between the expression of hepatic but not testicular enzyme with androstenone deposition in pig adipose tissue Sus scrofa
-
testis
-
Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
androstenone concentration in different tissues, overview Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
androstenone + NADH
-
Sus scrofa beta-androstenol + NAD+
-
?
additional information relationship between the expression of hepatic but not testicular enzyme with androstenone deposition in pig adipose tissue, overview Sus scrofa ?
-
?
additional information bifunctional enzyme that also catalyzes the reaction of the DELTA-5-3-ketosteroid isomerase, EC 5.3.3.1 Sus scrofa ?
-
?

Synonyms

Synonyms Comment Organism
3beta-HSD
-
Sus scrofa
3beta-hydroxysteroid dehydrogenase
-
Sus scrofa

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NADH
-
Sus scrofa