Inhibitors | Comment | Organism | Structure |
---|---|---|---|
monooctyltin | 0.081 mM, 50% inhibition; inhibition mechanism, overview | Rattus norvegicus | |
tributyltin | 0.012 mM, almost complete loss of activity; complete inhibition at 0.012 mM, the inhibition mechanism is not entirely competitive, overview | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00042 | - |
dehydroepiandrosterone | pH 7.5, 37°C | Rattus norvegicus | |
0.00059 | - |
dehydroepiandrosterone | 37°C, pH 8.4 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dehydroepiandrosterone + NADH + H+ | Rattus norvegicus | - |
androsterone + NAD+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dehydroepiandrosterone + NAD+ | - |
Rattus norvegicus | ? | - |
r | |
dehydroepiandrosterone + NADH + H+ | - |
Rattus norvegicus | androsterone + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3beta-HSD | - |
Rattus norvegicus |
3beta-hydroxysteroid dehydrogenase | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics | Rattus norvegicus | |
0.0027 | - |
tributyltin | pH 7.5, 37°C | Rattus norvegicus | |
0.0027 | - |
tributyltin | 37°C, pH 8.4 | Rattus norvegicus |