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BRENDA support

Literature summary for 1.1.1.141 extracted from

  • Gram, A.; Buechler, U.; Boos, A.; Hoffmann, B.; Kowalewski, M.P.
    Biosynthesis and degradation of canine placental prostaglandins: prepartum changes in expression and function of prostaglandin F2?-synthase (PGFS, AKR1C3) and 15-hydroxyprostaglandin dehydrogenase (HPGD) (2013), Biol. Reprod., 89, 2-2.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris E2QX67
-
-

Source Tissue

Source Tissue Comment Organism Textmining
corpus luteum
-
Canis lupus familiaris
-
placenta
-
Canis lupus familiaris
-
uterus
-
Canis lupus familiaris
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prostaglandin E2 + NAD+
-
Canis lupus familiaris 15-oxoprostaglandin E2 + NADH + H+
-
?
prostaglandin F2alpha + NAD+
-
Canis lupus familiaris 15-oxoprostaglandin F2alpha + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
HPGD
-
Canis lupus familiaris

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Canis lupus familiaris

Expression

Organism Comment Expression
Canis lupus familiaris levels enzyme mRNA increase significantly reaching the highest mRNA levels during the postimplantation period of pregnancy up