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Literature summary for 1.1.1.141 extracted from
- Endogenous inhibitors of human placental prostaglandin dehydrogenase (1992), Prostaglandins Leukot. Essent. Fatty Acids, 46, 241-245.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| hexadecanoic acid | 0.01 mM | Homo sapiens |  |
| mixture of endogenous fatty acids | mixture contains palmitic acid, stearic acid linoleic acid and oleic acid, competitive vs. prostaglandine E2 | Homo sapiens | |
| octadecanoic acid | 0.01 mM | Homo sapiens | |
| tetradecanoic acid | 0.01 mM | Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0117 | - |
prostaglandin E2 | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| placenta | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 12.15 | - |
enzyme from placenta | Homo sapiens |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | 0.0189, endogenous mixture of palmitic, stearic, oleic and linoleic acid | Homo sapiens |
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Release 2023.1 (January 2023)
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