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Literature summary for 1.1.1.140 extracted from
- Sorbitol synthesis by an engineered Lactobacillus casei strain expressing a sorbitol-6-phosphate dehydrogenase gene within the lactose operon (2005), FEMS Microbiol. Lett., 249, 177-183.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene gutF, construction of an overexpressing strain by gene insertion in the chromosomal lactose operon of strain BL155 resulting in strain BL232, subcloning in Escherichia coli strain DH5alpha | Lacticaseibacillus casei |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-sorbitol 6-phosphate + NAD+ | Lacticaseibacillus casei | - |
D-fructose 6-phosphate + NADH + H+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Lacticaseibacillus casei | - |
gene gutF | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
activities of different recombinant strains | Lacticaseibacillus casei |
| 0.182 | - |
strain BL232, grown on lactose, forward reaction | Lacticaseibacillus casei |
| 0.222 | - |
strain BL232, grown on lactose, reverse reaction | Lacticaseibacillus casei |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-sorbitol 6-phosphate + NAD+ | - |
Lacticaseibacillus casei | D-fructose 6-phosphate + NADH + H+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| D-sorbitol-6-phosphate dehydrogenase | - |
Lacticaseibacillus casei |
| sorbitol-6-phosphate dehydrogenase | - |
Lacticaseibacillus casei |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
reverse reaction | Lacticaseibacillus casei |
| 8.5 | - |
forward reaction | Lacticaseibacillus casei |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Lacticaseibacillus casei | |
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Release 2023.1 (January 2023)
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