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Literature summary for 1.1.1.133 extracted from

  • Kang, Y.; Yang, Y.; Lee, K.; Lee, S.; Sohng, J.K.; Lee, H.C.; Liou, K.; Kim, B.
    Preparative synthesis of dTDP-L-rhamnose through combined enzymatic pathways (2005), Biotechnol. Bioeng., 93, 21-27.
    View publication on PubMed

Application

Application Comment Organism
synthesis six enzymes, including the dTDP-4-keto-rhamnose reductase, are involved in the pathway and are prepared by recombinant expression in Escherichia coli for large scale production of O-antigen precursor sTDP-L-rhamnose in a one-pot reaction, overview Mesorhizobium loti

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Mesorhizobium loti

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dTDP-6-deoxy-L-mannose + NADP+ Mesorhizobium loti
-
dTDP-4-dehydro-6-deoxy-L-mannose + NADPH
-
?

Organism

Organism UniProt Comment Textmining
Mesorhizobium loti
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dTDP-6-deoxy-L-mannose + NADP+
-
Mesorhizobium loti dTDP-4-dehydro-6-deoxy-L-mannose + NADPH
-
?

Synonyms

Synonyms Comment Organism
dTDP-4-keto-rhamnose reductase
-
Mesorhizobium loti

Cofactor

Cofactor Comment Organism Structure
NADP+
-
Mesorhizobium loti