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Literature summary for 1.1.1.112 extracted from

  • Billings, R.E.; Sullivan, H.R.; McMahon, R.E.
    The dehydrogenation of 1-indanol by a soluble oxidoreductase from bovine liver (1971), J. Biol. Chem., 246, 3512-3517.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline 1 mM, 19% inhibition Bos taurus
2,2'-bipyridine 1 mM, 30% inhibition Bos taurus
8-hydroxyquinoline 1 mM, 84% inhibition, 0.1 mM, 40% inhibition Bos taurus
pyrazole 1 mM, 39% inhibition Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ammonium sulfate, CM-cellulose, Sephadex G-75, Sephadex G-100 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Bos taurus
-
kidney
-
Bos taurus
-
liver
-
Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.74
-
-
Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-acenaphthenol + NAD(P)+ 195% activity compared to indan-(RS)-1-ol Bos taurus 1-acenaphthenone + NAD(P)H
-
?
1-tetralol + NAD(P)+ 195% activity compared to indan-(RS)-1-ol Bos taurus 1-tetralone + NAD(P)H
-
?
9-fluorenol + NAD(P)+ 112% activity compared to indan-(RS)-1-ol Bos taurus 9-fluorenone + NAD(P)H
-
?
benzosuberol + NAD(P)+ 12% activity compared to indan-(RS)-1-ol Bos taurus benzosuberone + NAD(P)H
-
?
cyclohexen-3-ol + NAD(P)+ 103% activity compared to indan-(RS)-1-ol Bos taurus cyclohexen-3-one + NAD(P)H
-
?
indan-(RS)-1-ol + NAD(P)+
-
Bos taurus indan-1-one + NAD(P)H 100% activity ?
indan-(S)-1-ol + NAD(P)+ 171% activity compared to indan-(RS)-1-ol Bos taurus indan-1-one + NAD(P)H
-
?
trans-acenaphthene-1,2-diol + NAD(P)+ 100% activity compared to indan-(RS)-1-ol Bos taurus acenaphtene-1,2-dione + NAD(P)H
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9 10 cofactor NAD+ Bos taurus
10 10.5 cofactor NADP+ Bos taurus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Bos taurus
NADP+
-
Bos taurus