Literature summary for 1.1.1.1 extracted from

Cederlund, E.; Hedlund, J.; Hjelmqvist, L.; Jonsson, A.; Shafqat, J.; Norin, A.; Keung, W.M.; Persson, B.; Joernvall, H.
Characterization of new medium-chain alcohol dehydrogenases adds resolution to duplications of the class I/III and the sub-class I genes (2011), Chem. Biol. Interact., 191, 8-13.

Search for more literature for 1.1.1.1

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.6	-	Octanol	pH and temperature not specified in the publication	Scyliorhinus canicula

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
40000	-	x * 40000, SDS-PAGE	Scyliorhinus canicula

Organism

Organism	UniProt	Comment	Textmining
Columba livia	P86883	-	-
Scyliorhinus canicula	P86884	-	-

Purification (Commentary)

Purification (Comment)	Organism
native enzyme from liver by anion exchange and AMP affinity chromatography, and a second different step of anion exchange chromatography	Scyliorhinus canicula

Source Tissue

Source Tissue	Comment	Organism	Textmining
intestine	class III ADH	Scyliorhinus canicula	-
liver	-	Columba livia	-
liver	class III ADH	Scyliorhinus canicula	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
octanol + NAD+	-	Columba livia	octanal + NADH + H+	-	?
octanol + NAD+	-	Scyliorhinus canicula	octanal + NADH + H+	-	r

Subunits

Subunits	Comment	Organism
?	x * 40000, SDS-PAGE	Scyliorhinus canicula

Synonyms

Synonyms	Comment	Organism
ADH class III	-	Scyliorhinus canicula
class I ALDH	-	Columba livia

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
3.17	-	Octanol	pH and temperature not specified in the publication	Scyliorhinus canicula

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Columba livia

General Information

General Information	Comment	Organism
evolution	the class I type enzyme belongs to the medium-chain alcohol dehydrogenases, structural and evolutionary relationships of the pigeon enzyme, phylogenetic tree, overview	Columba livia
evolution	the class III type enzyme belongs to the medium-chain alcohol dehydrogenases, structural and evolutionary relationships of the dogfish enzyme, phylogenetic tree, overview	Scyliorhinus canicula

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Release 2023.1 (January 2023)