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BRENDA support

Literature summary for 1.1.1.1 extracted from

  • Langeland, B.T.; Morris, D.L.; McKinley-McKee, J.S.
    Metal binding properties of thiols: complexes with horse liver alcohol dehydrogenase (1999), Comp. Biochem. Physiol. B, 123, 155-162.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1,2-dithioglycerol competitive Equus caballus
1,2-Ethanedithiol competitive Equus caballus
1,3-propanedithiol competitive Equus caballus
1,4-Butanedithiol competitive Equus caballus
1,4-dithioerythritol competitive Equus caballus
1,4-dithiothreitol competitive Equus caballus
1-hydroxypyridine-2-thione competitive Equus caballus
1-thio-1-phenylmethane competitive Equus caballus
1-thioacetamide competitive Equus caballus
1-thioacetate competitive Equus caballus
1-thiobutane competitive Equus caballus
1-thioethane competitive Equus caballus
1-thioglycerol competitive Equus caballus
1-thiopropane competitive Equus caballus
1-thiosorbitol competitive Equus caballus
2-mercapto-1-methylimidazole competitive Equus caballus
2-mercaptobenzimidazole competitive Equus caballus
2-mercaptobenzothiazole competitive Equus caballus
2-mercaptoethanol competitive Equus caballus
2-mercaptoimidazole competitive Equus caballus
2-phenylethanethiol competitive Equus caballus
2-pyridylethanethiol competitive Equus caballus
2-thioacetate competitive Equus caballus
2-thiobutane competitive Equus caballus
2-thiopropane competitive Equus caballus
2-thiopyridine competitive Equus caballus
2-thiopyrimidine competitive Equus caballus
3-mercapto-1,2,4-triazole competitive Equus caballus
3-thiopropionate competitive Equus caballus
6-thioguanine competitive Equus caballus
6-thioguanosine competitive Equus caballus
captopril competitive Equus caballus
coenzyme A competitive Equus caballus
Cys competitive Equus caballus
cysteamine competitive Equus caballus
diethyldithiocarbamate competitive Equus caballus
Disulfiram competitive Equus caballus
glutathione competitive Equus caballus
additional information thiols and dithiols have their main effect, at the enzyme-NAD+-thiol complex level, by competition with alcohol for the catalytic zinc Equus caballus
Penicillamine competitive Equus caballus
Thiophenol competitive Equus caballus
Thiourea competitive Equus caballus

Organism

Organism UniProt Comment Textmining
Equus caballus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Equus caballus
-

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Equus caballus
NADH
-
Equus caballus