Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-Methylpyrazole | class III enzyme is completely insensitive to inhibition | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.056 | - |
12-Hydroxydodecanoic acid | - |
Homo sapiens | |
0.55 | - |
1-Octanol | - |
Homo sapiens | |
27 | - |
1-Pentanol | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
x * 40000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
class III isoenzyme | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | the class III enzyme contributes by far the bulk of the total alcohol dehydrogenase activity | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
12-hydroxydodecanoate + NAD+ | - |
Homo sapiens | 12-oxododecanoic acid + NADH | - |
? | |
ethanol + NAD+ | no oxidation with class III enzyme | Homo sapiens | acetaldehyde + NADH | - |
? | |
methanol + NAD+ | no activity with class III enzyme | Homo sapiens | formaldehyde + NADH + H+ | - |
? | |
octan-1-ol + NAD+ | - |
Homo sapiens | n-octanal + NADH | - |
? | |
pentanol + NAD+ | - |
Homo sapiens | n-pentanal + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 40000, SDS-PAGE | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.183 | - |
1-Pentanol | - |
Homo sapiens | |
0.333 | - |
12-Hydroxydodecanoic acid | - |
Homo sapiens | |
2.83 | - |
1-Octanol | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens | |
NADH | - |
Homo sapiens |