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Information on EC 2.6.1.24 - diiodotyrosine transaminase

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EC Tree
     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.24 diiodotyrosine transaminase
IUBMB Comments
A pyridoxal-phosphate protein. Also acts on 3,5-dichloro-, 3,5-dibromo- and 3-iodo-L-tyrosine, thyroxine and triiodothyronine.
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The expected taxonomic range for this enzyme is: Rattus norvegicus
Synonyms
aminotransferase, diiodotyrosine, diiodotyrosine aminotransferase, EC 2.6.1.25, halogenated tyrosine aminotransferase, halogenated tyrosine transaminase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3,5-diiodo-L-tyrosine + 2-oxoglutarate = 4-hydroxy-3,5-diiodophenylpyruvate + L-glutamate
show the reaction diagram
also acts on 3,5-dichloro-, 3,5-dibromo- and 3-iodo-L-tyrosine, thyroxine and triiodothyronine
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