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The enzyme appears in viruses and cellular organisms
Synonyms
phosphorylase, urate ribonucleotide, UAR phosphorylase, urate ribonucleotide phosphorylase, urate-ribonucleotide:orthophosphate D-ribosyltransferase,
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phosphorylase, urate ribonucleotide
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UAR phosphorylase
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urate ribonucleotide phosphorylase
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urate-ribonucleotide:orthophosphate D-ribosyltransferase
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urate D-ribonucleoside + phosphate = urate + alpha-D-ribose 1-phosphate
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pentosyl group transfer
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urate-D-ribonucleoside:phosphate alpha-D-ribosyltransferase
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uric acid ribonucleoside + arsenate
urate + D-ribose 1-phosphate
uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
uric acid ribonucleoside + arsenate
urate + D-ribose 1-phosphate
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reverse reaction not demonstrated, arsenate can replace phosphate at a lower reaction rate
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ir
uric acid ribonucleoside + arsenate
urate + D-ribose 1-phosphate
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uric acid ribonucleoside + arsenate
urate + D-ribose 1-phosphate
Pigeon
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uric acid ribonucleoside + arsenate
urate + D-ribose 1-phosphate
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uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
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ir
uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
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uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
Pigeon
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uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
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uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
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ir
uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
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uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
Pigeon
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uric acid ribonucleoside + phosphate
urate + D-ribose 1-phosphate
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1-Ribosyluracil
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1 mM, about 85% inhibition
2-thio-6-oxopurine
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1 mM, 73% inhibition
2-Thiouracil
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1 mM, 96% inhibition
4-amino-5-imidazolecarboxamide
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1 mM, about 15% inhibition
5-methyluracil
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1 mM, about 90% inhibition
5-methyluridine
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1 mM, about 95% inhibition
Colchicine
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1 mM, 43% inhibition, competitive
guanosine
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1 mM, about 20% inhibition
Inosine
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1 mM, about 25% inhibition
p-chloromercuribenzoate
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reversed by cysteine
Phenylbutazone
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1 mM, 30% inhibition, competitive
Uracil
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1 mM, about 85% inhibition
xanthine
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1 mM, 35% inhibition
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1.23
Colchicine
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37°C, pH 8.2
1.76
Phenylbutazone
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37°C, pH 8.2
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7.5 - 8
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reaction with phosphate or arsenate
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6 - 9.5
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pH 6.0: about 60% of maximal activity, pH 9.5: 45% of maximal activity
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brenda
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brenda
Pigeon
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brenda
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brenda
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brenda
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low activity
brenda
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brenda
Pigeon
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brenda
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brenda
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brenda
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brenda
Pigeon
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brenda
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brenda
Pigeon
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brenda
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brenda
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brenda
Pigeon
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brenda
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brenda
Pigeon
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brenda
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brenda
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4.5
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0°C, 10 min, 30% loss of activity, partially purified enzyme
639636
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50
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pH 7.8, 5 min, 5% loss of activity, partially purified enzyme
60
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pH 7.8, 5 min, 40% loss of activity, partially purified enzyme
70
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pH 7.8, 5 min, 95% loss of activity, partially purified enzyme
80
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pH 7.8, 5 min, 100% loss of activity, partially purified enzyme
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-10°C, partially purified enzyme is stable for at least 2 months
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Laster, L.; Blair, A.
An intestinal phosphorylase for uric ribonucleoside
J. Biol. Chem.
238
3348-3357
1963
Canis lupus familiaris, Cavia porcellus, Pigeon, Rattus norvegicus
brenda
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