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Information on EC 2.4.1.122 - N-acetylgalactosaminide beta-1,3-galactosyltransferase

for references in articles please use BRENDA:EC2.4.1.122
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IUBMB Comments
The eukaryotic enzyme can act on non-reducing O-serine-linked N-acetylgalactosamine residues in mucin glycoproteins, forming the T-antigen. The bacterial enzyme, found in some pathogenic strains, is involved in biosynthesis of the O-antigen repeating unit.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
galactosyltransferase, c1galt1, t-synthase, beta-galactosyltransferase, c1galt, core 1 synthase, dc1galt1, core 1 beta3-gal-t, ce-t-synthase, core 1 beta3-gal-transferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-galactose + N-acetyl-alpha-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R
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