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Information on EC 1.14.11.44 - (R)-dichlorprop dioxygenase (2-oxoglutarate)

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EC Tree
IUBMB Comments
Fe2+-dependent enzyme. The enzymes from the Gram-negative bacteria Delftia acidovorans MC1 and Sphingomonas herbicidovorans MH are involved in the degradation of the (R)-enantiomer of the phenoxyalkanoic acid herbicides mecoprop and dichlorprop [1,2].
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
aad-1, (r)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, alpha-ketoglutarate-dependent (r)-dichlorprop dioxygenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + pyruvate + succinate + CO2
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(2)
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(R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 4-chloro-2-methylphenol + pyruvate + succinate + CO2
show the reaction diagram
(1)
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