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Information on EC 1.1.1.309 - phosphonoacetaldehyde reductase (NADH)

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IUBMB Comments
The enzyme from Streptomyces viridochromogenes catalyses a step in the biosynthesis of phosphinothricin tripeptide, the reduction of phosphonoacetaldehyde to 2-hydroxyethylphosphonate. The preferred cofactor is NADH, lower activity with NADPH .
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The enzyme appears in viruses and cellular organisms
Synonyms
PhpC, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-hydroxyethylphosphonate + NAD+ = phosphonoacetaldehyde + NADH + H+
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