1.1.3.38: vanillyl-alcohol oxidase
This is an abbreviated version!
For detailed information about vanillyl-alcohol oxidase, go to the full flat file.
Word Map on EC 1.1.3.38
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1.1.3.38
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opacification
-
simplicissimum
-
ostium
-
veratryl
-
flavinylation
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vertebrobasilar
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aphakia
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p-quinone
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logmar
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argan
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4-ethylphenol
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4-alkylphenols
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synthesis
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analysis
- 1.1.3.38
-
opacification
- simplicissimum
-
ostium
-
veratryl
-
flavinylation
-
vertebrobasilar
- aphakia
- p-quinone
-
logmar
-
argan
- 4-ethylphenol
- 4-alkylphenols
- synthesis
- analysis
Reaction
Synonyms
4-allylphenol oxidase, 4-hydroxy-2-methoxybenzyl alcohol oxidase, Aryl-alcohol oxidase, EUGO, HMFO, Oxidase, vanillyl alcohol, RHA1_ro03282, vanillyl-alcohol oxidase, VAO, VAOA
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Inhibitors
Inhibitors on EC 1.1.3.38 - vanillyl-alcohol oxidase
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4-(1-Heptenyl)-phenol
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the crystal structure of the enzyme in complex with the inhibitor shows that the catalytic cavity is completely filled by the inhibitor
cinnamyl alcohol
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strong competitive inhibitor of vanillyl-alcohol oxidation
p-mercuribenzoate
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one Cys residue reacts rapidly without loss of enzyme activity, three sulfhydryl groups then react in an 'all or none process' involving enzyme inactivation and dissociation of the octamer into dimers, antichaotropic salts protect from mercuration
isoeugenol
competitive inhibitor, isoeugenol is predominantly in its deprotonated form when bound to wild-type VAOA, but predominantly in its protonated form when bound to the variants Y108F or Y503F