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1.1.3.15: (S)-2-hydroxy-acid oxidase

This is an abbreviated version!
For detailed information about (S)-2-hydroxy-acid oxidase, go to the full flat file.

Word Map on EC 1.1.3.15

Reaction

an (S)-2-hydroxy carboxylate
+
O2
=
a 2-oxo carboxylate
+
H2O2

Synonyms

(L)-2-HAOX, (S)-2-hydroxy-acid oxidase, peroxisomal, 2-hydroxy acid oxidase, CSUB_C1080, EC 1.1.3.1, GLO, Glo1, GLO3, Glo4, glycolate oxidase, GO, GO1, GOX, GOX1, GOX2, HAO1, Hao2, HAOX, HAOX1, HAOX2, HAOX3, hydroxy-acid oxidase A, hydroxy-acid oxidase B, hydroxyacid oxidase 1, hydroxyacid oxidase A, L-2-hydroxy acid oxidase, L-2-hydroxyacid oxidase A, L-alpha-hydroxy acid oxidase, L-amino acid oxidase, L-LAC-OX, L-lactate monooxygenase, L-lactate oxidase, L-LOx, lactate oxidase, LCHAO, LctO, lHAOX1, lHAOX2, long chain hydroxy acid oxidase, long chain l-2-hydroxy acid oxidase, long chain L-2-hydroxy acid oxidase 2, long-chain 2-hydroxy acid oxidase, long-chain L-alpha-hydroxy acid oxidase, LOX, More, NbS00005125g0015, NbS00060838g0004, Nbv5tr6245008, Os03g0786100, Os04g0623500, Os07g0616500, oxidase, L-2-hydroxy acid, RCOM_0631490, RCOM_0684800

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.15 (S)-2-hydroxy-acid oxidase

Reference

Reference on EC 1.1.3.15 - (S)-2-hydroxy-acid oxidase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Jones, J.M.; Morrell, J.C.; Gould, S.J.
Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases
J. Biol. Chem.
275
12590-12597
2000
Homo sapiens, Rattus sp.
Manually annotated by BRENDA team
Iwamoto, K.; Ikawa, T.
A novel glycolate oxidase requiring flavin mononucleotide as the cofactor in the Prasinophycean alga Mesostigma viride
Plant Cell Physiol.
41
988-991
2000
Mesostigma viride
Manually annotated by BRENDA team
Ferjancic-Biagini, A.; Dupuis, L.; De Caro, J.; Puigserver, A.
Inhibitory effects of anions and active site amino acid sequence of chicken liver L-2-hydroxyacid oxidase A, a member of the FMN-dependent alpha-hydroxy acid oxidizing enzyme family
Biochimie
80
1047-1054
1998
Gallus gallus
Manually annotated by BRENDA team
Stenberg, K.; Lindqvist, Y.
Three-dimensional structures of glycolate oxidase with bound active-site inhibitors
Protein Sci.
6
1009-1015
1997
Spinacia oleracea
Manually annotated by BRENDA team
Payne, M.S.; Petrillo, K.L.; Gavagan, J.E.; DiCosimo, R.; Wagner, L.W.; Anton, D.L.
Engineering Pichia pastoris for biocatalysis: co-production of two active enzymes
Gene
194
179-182
1997
Spinacia oleracea
Manually annotated by BRENDA team
Belmouden, A.; Lederer, F.
The role of a beta barrel loop 4 extension in modulating the physical and functional properties of long-chain 2-hydroxy-acid oxidase isozymes
Eur. J. Biochem.
238
790-798
1996
Rattus sp.
Manually annotated by BRENDA team
Stenberg, K.; Lindqvist, Y.
High-level expression, purification, and crystallization of recombinant spinach glycolate oxidase in Escherichia coli
Protein Expr. Purif.
8
295-298
1996
Spinacia oleracea
Manually annotated by BRENDA team
Payne, M.S.; Petrillo, K.L.; Gavagan, J.E.; Wagner, L.W.; DiCosimo, R.; Anton, D.L.
High-level production of spinach glycolate oxidase in the methylotrophic yeast Pichia pastoris: engineering a biocatalyst
Gene
167
215-219
1995
Spinacia oleracea
Manually annotated by BRENDA team
Sandalova, T.; Lindqvist, Y.
Crystal structure of apo-glycolate oxidase
FEBS Lett.
327
361-365
1993
Spinacia oleracea
Manually annotated by BRENDA team
Dupuis, L.; De Caro, J.; Brachet, P.; Puigserver, A.
Purification and some characteristics of chicken liver L-2-hydroxyacid oxidase A
FEBS Lett.
266
183-186
1990
Gallus gallus
Manually annotated by BRENDA team
Urban, P.; Chirat, I.; Lederer, F.
Rat kidney L-2-hydroxyacid oxidase. Structural and mechanistic comparison with flavocytochrome b2 from bakerÆs yeast
Biochemistry
27
7365-7371
1988
Rattus sp.
Manually annotated by BRENDA team
Gunshore, S.; Brush, E.J.; Hamilton, G.A.
Equilibrium constants for the formation of glyoxylate thiohemiacetals and kinetic constants for their oxidation by O2 catalyzed by L-hydroxy acid oxidase
Bioorg. Chem.
13
1-13
1985
Rattus sp.
-
Manually annotated by BRENDA team
Tolbert, N.E.
Metabolic pathways in peroxisomes and glyoxysomes
Annu. Rev. Biochem.
50
133-157
1981
Mammalia, plant, Rattus sp.
Manually annotated by BRENDA team
Brush, E.J.; Hamilton, G.A.
Thiol-glyoxylate adducts as substrates for rat kidney L-alpha-hydroxy acid oxidase
Biochem. Biophys. Res. Commun.
103
1194-1200
1981
Rattus sp.
Manually annotated by BRENDA team
Phillips, D.R.; Duley, J.A.; Fennell, D.J.; Holmes, R.S.
The self-association of L-alpha-hydroxyacid oxidase
Biochim. Biophys. Acta
427
679-687
1976
Rattus sp.
Manually annotated by BRENDA team
Duley, J.A.; Holmes, R.S.
L-alpha-hydroxyacid oxidase isozymes. Purification and properties
Eur. J. Biochem.
63
163-173
1976
Mus musculus, Rattus sp.
Manually annotated by BRENDA team
Cromartie, T.H.; Walsh, C.T.
Rat kidney L-alpha-hydroxy acid oxidase: Isolation of enzyme with one flavine coenzyme per two subunits
Biochemistry
14
2588-2596
1975
Rattus sp.
Manually annotated by BRENDA team
Cromartie, T.H.; Walsh, C.
Mechanistic studies on the rat kidney flavoenzyme L-alpha-hydroxy acid oxidase
Biochemistry
14
3482-3490
1975
Rattus sp.
Manually annotated by BRENDA team
Domenech, S.E.; Machado De Domenech, E.E.; Blanco, A.
Molecular forms of L-alpha-hydroxy acid oxidase from rat kidney
Biochim. Biophys. Acta
321
54-63
1973
Rattus sp.
Manually annotated by BRENDA team
Ushijima, Y.
Identity of aliphatic L-alpha-hydroxyacid oxidase and glycolate oxidase from rat liver
Arch. Biochem. Biophys.
155
361-367
1973
Rattus sp.
Manually annotated by BRENDA team
Schuman, M.; Massey, V.
Effect of anions on the catalytic activity of pig liver glycolic acid oxidase
Biochim. Biophys. Acta
227
521-537
1971
Sus scrofa
Manually annotated by BRENDA team
Schuman, M.; Massey, V.
Purification and characterization of glycolic acid oxidase from pig liver
Biochim. Biophys. Acta
227
500-520
1971
Sus scrofa
Manually annotated by BRENDA team
Scott, P.J.; Visentin, L.P.; Allen, J.M.
The enzymatic characteristics of peroxisomes of amphibian and avian liver and kidney
Ann. N. Y. Acad. Sci.
168
244-264
1969
Gallus gallus, Lithobates pipiens
Manually annotated by BRENDA team
Nakano, M.; Ushijima, Y.; Saga, M.; Tsutsumi, Y.; Asami, H.
Aliphatic L-alpha-hydroxyacid oxidase from rat livers. Purification and properties
Biochim. Biophys. Acta
167
9-22
1968
Rattus sp.
Manually annotated by BRENDA team
Eichel, H.J.
Oxidation of L-alpha-hydroxy acids by Tetrahymena pyriformis
Biochim. Biophys. Acta
128
183-186
1966
Tetrahymena pyriformis
Manually annotated by BRENDA team
Nakano, M.; Danowski, T.S.
Crystalline mammalian L-amino acid oxidase from rat kidney mitochondria
J. Biol. Chem.
241
2075-2083
1966
Rattus sp.
Manually annotated by BRENDA team
Robinson, J.C.; Keay, L.; Molinari, R.; Sizer, I.W.
L-alpha-Hydroxy acid oxidases of hog renal cortex
J. Biol. Chem.
237
2001-2010
1962
Sus scrofa
Manually annotated by BRENDA team
Frigerioo, N.A.; Harbury, H.A.
Preparation and some properties of crystalline glycolic acid oxidase of spinach
J. Biol. Chem.
231
135-157
1958
Spinacia oleracea
Manually annotated by BRENDA team
Kun, E.; Dechary, J.M.; Pitot, H.C.
The oxidation of glycolic acid by a liver enzyme
J. Biol. Chem.
210
269-280
1954
Rattus sp.
Manually annotated by BRENDA team
Streitenberger, S.A.; Lopez-Mas, J.A.; Sanchez-Ferrer, A.; Garcia-Carmona, F.
Use of dye affinity chromatography for the purification of Aerococcus viridans lactate oxidase
Biotechnol. Prog.
18
657-659
2002
Aerococcus viridans
Manually annotated by BRENDA team
Streitenberger, S.A.; Lopez-Mas, J.A.; Sanchez-Ferrer, A.; Garcia-Carmona, F.
Non-linear slow-binding inhibition of Aerococcus viridans lactate oxidase by Cibacron Blue 3GA
J. Enzyme Inhib.
16
301-312
2001
Aerococcus viridans
Manually annotated by BRENDA team
Yorita, K.; Matsuoka, T.; Misaki, H.; Massey, V.
Interaction of two arginine residues in lactate oxidase with the enzyme flavin: Conversion of FMN to 8-formyl-FMN
Proc. Natl. Acad. Sci. USA
97
13039-13044
2000
Aerococcus viridans
Manually annotated by BRENDA team
Morimoto, Y.; Yorita, K.; Aki, K.; Misaki, H.; Massey, V.
L-Lactate oxidase from Aerococcus viridans crystallized as an octamer. Preliminary X-ray studies
Biochimie
80
309-312
1998
Aerococcus viridans
Manually annotated by BRENDA team
Yorita, K.; Janko, K.; Aki, K.; Ghisla, S.; Palfey, B.A.; Massey, V.
On the reaction mechanism of L-lactate oxidase: quantitative structure-activity analysis of the reaction with para-substituted L-mandelates
Proc. Natl. Acad. Sci. USA
94
9590-9595
1997
Aerococcus viridans
Manually annotated by BRENDA team
Sztajer, H.; Wang, W.; Luensdorf, H.; Stocker, A.; Schmid, R.D.
Purification and some properties of a novel microbial lactate oxidase
Appl. Microbiol. Biotechnol.
45
600-606
1996
Geotrichum candidum
Manually annotated by BRENDA team
Maeda-Yorita, K.; Aki, K.; Sagai, H.; Misaki, H.; Massey, V.
L-Lactate oxidase and L-lactate monooxygenase: mechanistic variations on a common structural theme
Biochimie
77
631-642
1995
Aerococcus viridans
Manually annotated by BRENDA team
Massey, V.; Ghisla, S.; Kieschke, K.
Studies on the reaction mechanism of lactate oxidase. Formation of two covalent flavin-substrate adducts on reaction with glycollate
J. Biol. Chem.
255
2796-2806
1980
Mycolicibacterium smegmatis
Manually annotated by BRENDA team
Yorita, K.; Aki, K.; Ohkuma-Soyejima, T.; Kokubo, T.; Misaki, H.; Massey, V.
Conversion of L-lactate oxidase to a long chain alpha-hydroxyacid oxidase by site-directed mutagenesis of alanine 95 to glycine
J. Biol. Chem.
271
28300-28305
1996
Aerococcus viridans
Manually annotated by BRENDA team
Wang, W.J.; Huang, J.Q.; Yang, C.; Huang, J.J.; Li, M.Q.
The recognition of glycolate oxidase apoprotein with flavin analogs in higher plants
Acta Biochim. Biophys. Sin.
36
290-296
2004
Brassica rapa subsp. oleifera, Carica papaya, Cucumis sativus, Nicotiana tabacum, Oryza sativa, Spinacia oleracea, Triticum aestivum, Vigna unguiculata, Zea mays
Manually annotated by BRENDA team
Recalcati, S.; Tacchini, L.; Alberghini, A.; Conte, D.; Cairo, G.
Oxidative stress-mediated down-regulation of rat hydroxyacid oxidase 1, a liver-specific peroxisomal enzyme
Hepatology
38
1159-1166
2003
Rattus norvegicus
Manually annotated by BRENDA team
Popov, V.N.; Dmitrieva, E.A.; Eprintsev, A.T.; Igamberdiev, A.U.
Glycolate oxidase isoforms are distributed between the bundle sheath and mesophyll tissues of maize leaves
J. Plant Physiol.
160
851-857
2003
Zea mays
Manually annotated by BRENDA team
Jin, J.; Tan, T.; Wang, H.; Su, G.
The expression of spinach glycolate oxidase (GO) in E. coli and the application of GO in the production of glyoxylic acid
Mol. Biotechnol.
25
207-214
2003
Spinacia oleracea
Manually annotated by BRENDA team
Zhang, J.; Xing, G.M.; Yan, Z.Y.; Li, Z.X.
beta-N-Oxalyl-L-a,b-diaminopropionic acid protects the activity of glycolate oxidase in Lathyrus sativus seedlings under high light
Russ. J. Plant Physiol.
50
618-622
2003
Lathyrus sativus
-
Manually annotated by BRENDA team
Seki, M.; Iida, K.; Saito, M.; Nakayama, H.; Yoshida, S.
Hydrogen peroxide production in Streptococcus pyogenes: involvement of lactate oxidase and coupling with aerobic utilization of lactate
J. Bacteriol.
186
2046-2051
2004
Streptococcus pyogenes
Manually annotated by BRENDA team
Streitenberger, S.A.; Lopez-Mas, J.A.; Sanchez-Ferrer, A.; Garcia-Carmona, F.
A study on the kinetic mechanism of apoenzyme reconstitution from Aerococcus viridans lactate oxidase
J. Enzyme Inhib. Med. Chem.
18
285-288
2003
Aerococcus viridans
Manually annotated by BRENDA team
Umena, Y.; Yorita, K.; Matsuoka, T.; Abe, M.; Kita, A.; Fukui, K.; Tsukihara, T.; Morimoto, Y.
Crystallization and preliminary X-ray diffraction study of L-lactate oxidase (LOX), R181M mutant, from Aerococcus viridans
Acta Crystallogr. Sect. F
61
439-441
2005
Aerococcus viridans
Manually annotated by BRENDA team
Leiros, I.; Wang, E.; Rasmussen, T.; Oksanen, E.; Repo, H.; Petersen, S.B.; Heikinheimo, P.; Hough, E.
The 2.1 A structure of Aerococcus viridans L-lactate oxidase (LOX)
Acta Crystallogr. Sect. F
F62
1185-1190
2006
Aerococcus viridans
Manually annotated by BRENDA team
Umena, Y.; Yorita, K.; Matsuoka, T.; Kita, A.; Fukui, K.; Morimoto, Y.
The crystal structure of L-lactate oxidase from Aerococcus viridans at 2.1 A resolution reveals the mechanism of strict substrate recognition
Biochem. Biophys. Res. Commun.
350
249-256
2006
Aerococcus viridans
Manually annotated by BRENDA team
Cunane, L.M.; Barton, J.D.; Chen, Z.W.; Le, K.H.; Amar, D.; Lederer, F.; Mathews, F.S.
Crystal structure analysis of recombinant rat kidney long chain hydroxy acid oxidase
Biochemistry
44
1521-1531
2005
Rattus norvegicus (Q07523)
Manually annotated by BRENDA team
Minagawa, H.; Yoshida, Y.; Kenmochi, N.; Furuichi, M.; Shimada, J.; Kaneko, H.
Improving the thermal stability of lactate oxidase by directed evolution
Cell. Mol. Life Sci.
64
77-81
2007
Aerococcus viridans
Manually annotated by BRENDA team
Lau, W.W.; Armbrust, E.V.
Detection of glycolate oxidase gene glcD diversity among cultured and environmental marine bacteria
Environ. Microbiol.
8
1688-1702
2006
Oceanimonas doudoroffii, Pseudomonas stutzeri, Roseobacter sp.
Manually annotated by BRENDA team
Zhou, F.; Wu, G.; Deng, W.; Pu, Y.; Wei, C.; Li, Y.
Interaction of rice dwarf virus outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8
FEBS Lett.
581
34-40
2007
Oryza sativa
Manually annotated by BRENDA team
Zhou, S.; Chen, F.; Nahashon, S.; Chen, T.
Cloning and characterization of glycolate oxidase and NADH-dependent hydroxypyruvate reductase genes in Pachysandra terminalis
HortScience
41
1226-1230
2006
Pachysandra terminalis (Q19U05)
-
Manually annotated by BRENDA team
Eprintsev, A.T.; Iventev, A.N.; Popov, V.N.
Distribution and properties of glycolate oxidase from bundle sheath and mesophyll cells of green amaranth leaves (Amaranthus retroflecsus)
Russ. J. Plant Physiol.
52
553-558
2005
Amaranthus retroflexus
-
Manually annotated by BRENDA team
Huang, J.J.; Wang, W.J.; Ye, J.Q.; Peng, X.X.
Glycerate-oxidizing activity of glycolate oxidase from leaves of Spinacia oleracea
Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao
32
183-188
2006
Spinacia oleracea
Manually annotated by BRENDA team
Kupletskaya, M.B.; Sukacheva, M.V.; Kurakov, A.V.; Netrusov, A.I.
Search for lactate oxidase producer microorganisms
Appl. Biochem. Microbiol.
43
178-181
2007
Geotrichum candidum
-
Manually annotated by BRENDA team
Vignaud, C.; Pietrancosta, N.; Williams, E.L.; Rumsby, G.; Lederer, F.
Purification and characterization of recombinant human liver glycolate oxidase
Arch. Biochem. Biophys.
465
410-416
2007
Homo sapiens
Manually annotated by BRENDA team
Li, S.J.; Umena, Y.; Yorita, K.; Matsuoka, T.; Kita, A.; Fukui, K.; Morimoto, Y.
Crystallographic study on the interaction of L-lactate oxidase with pyruvate at 1.9 Angstrom resolution
Biochem. Biophys. Res. Commun.
358
1002-1007
2007
Aerococcus viridans
Manually annotated by BRENDA team
Murray, M.S.; Holmes, R.P.; Lowther, W.T.
Active site and loop 4 movements within human glycolate oxidase implications for substrate specificity and drug design
Biochemistry
47
2439-2449
2008
Homo sapiens (Q9UJM8), Homo sapiens
Manually annotated by BRENDA team
Barre, O.; Mourlane, F.; Solioz, M.
Copper induction of lactate oxidase of Lactococcus lactis: a novel metal stress response
J. Bacteriol.
189
5947-5954
2007
Lactococcus lactis (Q9CG58), Lactococcus lactis, Lactococcus lactis IL1403 (Q9CG58), Lactococcus lactis IL1403
Manually annotated by BRENDA team
Taniai, H.; Iida, K.; Seki, M.; Saito, M.; Shiota, S.; Nakayama, H.; Yoshida, S.
Concerted action of lactate oxidase and pyruvate oxidase in aerobic growth of Streptococcus pneumoniae: role of lactate as an energy source
J. Bacteriol.
190
3572-3579
2008
Streptococcus pneumoniae
Manually annotated by BRENDA team
Furuichi, M.; Suzuki, N.; Dhakshnamoorhty, B.; Minagawa, H.; Yamagishi, R.; Watanabe, Y.; Goto, Y.; Kaneko, H.; Yoshida, Y.; Yagi, H.; Waga, I.; Kumar, P.K.; Mizuno, H.
X-ray structures of Aerococcus viridans lactate oxidase and its complex with D-lactate at pH 4.5 show an alpha-hydroxyacid oxidation mechanism
J. Mol. Biol.
378
436-446
2008
Aerococcus viridans
Manually annotated by BRENDA team
Parra, A.; Casero, E.; Lorenzo, E.; Pariente, F.; Vazquez, L.
Nanomechanical properties of globular proteins: lactate oxidase
Langmuir
23
2747-2754
2007
Pediococcus sp.
Manually annotated by BRENDA team
Romero, M.R.; Garay, F.; Baruzzi, A.M.
Design and optimization of a lactate amperometric biosensor based on lactate oxidase cross-linked with polymeric matrixes
Sens. Actuators B Chem.
B131
590-595
2008
Pediococcus sp.
-
Manually annotated by BRENDA team
Magnani, D.; Barre, O.; Gerber, S.D.; Solioz, M.
Characterization of the CopR regulon of Lactococcus lactis IL1403
J. Bacteriol.
190
536-545
2008
Lactococcus lactis (Q9CG58), Lactococcus lactis, Lactococcus lactis IL1403 (Q9CG58), Lactococcus lactis IL1403
Manually annotated by BRENDA team
Ballesta-Claver, J.; Valencia-Miron, M.C.; Capitan-Vallvey, L.F.
One-shot lactate chemiluminescent biosensor
Anal. Chim. Acta
629
136-144
2008
Pediococcus sp.
Manually annotated by BRENDA team
Nawawi, R.A.; Baiano, J.C.; Kvennefors, E.C.; Barnes, A.C.
Host-directed evolution of a novel lactate oxidase in Streptococcus iniae isolates from barramundi (Lates calcarifer)
Appl. Environ. Microbiol.
75
2908-2919
2009
Streptococcus iniae (A9QH69), Streptococcus iniae (A9QH71), Streptococcus iniae, Streptococcus iniae QMA0177 (A9QH71)
Manually annotated by BRENDA team
Pennati, A.; Gadda, G.
Involvement of ionizable groups in catalysis of human liver glycolate oxidase
J. Biol. Chem.
284
31214-31222
2009
Homo sapiens (Q9UJM8), Homo sapiens
Manually annotated by BRENDA team
Lowinsohn, D.; Bertotti, M.
A biosensor based on immobilization of lactate oxidase in a PB-CTAB film for FIA determination of lactate in beer samples
J. Braz. Chem. Soc.
19
637-642
2008
Pediococcus sp.
-
Manually annotated by BRENDA team
Xu, H.; Zhang, J.; Zeng, J.; Jiang, L.; Liu, E.; Peng, C.; He, Z.; Peng, X.
Inducible antisense suppression of glycolate oxidase reveals its strong regulation over photosynthesis in rice
J. Exp. Bot.
60
1799-1809
2009
Oryza sativa (Q10CE4), Oryza sativa
Manually annotated by BRENDA team
Fahnenstich, H.; Scarpeci, T.E.; Valle, E.M.; Fluegge, U.I.; Maurino, V.G.
Generation of hydrogen peroxide in chloroplasts of Arabidopsis overexpressing glycolate oxidase as an inducible system to study oxidative stress
Plant Physiol.
148
719-729
2008
Arabidopsis thaliana (Q56ZN0)
Manually annotated by BRENDA team
Zelitch, I.; Schultes, N.P.; Peterson, R.B.; Brown, P.; Brutnell, T.P.
High glycolate oxidase activity is required for survival of maize in normal air
Plant Physiol.
149
195-204
2009
Zea mays
Manually annotated by BRENDA team
Eprintsev, A.; Semenov, A.; Navid, M.; Popov, V.
Physical, chemical, and regulatory properties of glycolate oxidase in C3 and C4 plants
Russ. J. Plant Physiol.
56
164-167
2009
Glycine max, Zea mays
-
Manually annotated by BRENDA team
Yashina, E.I.; Borisova, A.V.; Karyakina, E.E.; Shchegolikhina, O.I.; Vagin, M.Y.; Sakharov, D.A.; Tonevitsky, A.G.; Karyakin, A.A.
Sol-gel immobilization of lactate oxidase from organic solvent: toward the advanced lactate biosensor
Anal. Chem.
82
1601-1604
2010
Pediococcus sp.
Manually annotated by BRENDA team
de Bari, L.; Valenti, D.; Atlante, A.; Passarella, S.
L-lactate generates hydrogen peroxide in purified rat liver mitochondria due to the putative L-lactate oxidase localized in the intermembrane space
FEBS Lett.
584
2285-2290
2010
Rattus norvegicus
Manually annotated by BRENDA team
Casero, E.; Petit-Dominguez, M.D.; Parra-Alfambra, A.M.; Gismera, M.J.; Pariente, F.; Lorenzo, E.; Vazquez, L.
One-step covalent microcontact printing approach to produce patterns of lactate oxidase
Phys. Chem. Chem. Phys.
12
2830-2837
2010
Pediococcus sp.
Manually annotated by BRENDA team
Kataky, R.; Zawawi, R.M.
Modification of the chiral selectivity of D-glucose oxidase and L-lactate oxidase in a collagen matrix
Phys. Chem. Chem. Phys.
12
9183-9187
2010
Pediococcus sp.
Manually annotated by BRENDA team
Barawkar, D.; Meru, A.; Bandyopadhyay, A.; Banerjee, A.; Deshpande, A.; Athare, C.; Koduru, C.; Khose, G.; Gundu, J.; Mahajan, K.; Patil, P.; Kandalkar, S.; Niranjan, S.; Bhosale, S.; De, S.; Mukhopadhyay, S.; Chaudhary, S.; Koul, S.; Singh, U.; Chugh, A.
Potent and selective inhibitors of long chain l-2-hydroxy acid oxidase reduced blood pressure in DOCA salt-treated rats
ACS Med. Chem. Lett.
2
919-923
2011
Rattus norvegicus
Manually annotated by BRENDA team
Liu, L.; Tong, H.; Dong, X.
Function of the pyruvate oxidase-lactate oxidase cascade in interspecies competition between Streptococcus oligofermentans and Streptococcus mutans
Appl. Environ. Microbiol.
78
2120-2127
2012
Streptococcus cristatus
Manually annotated by BRENDA team
Barawkar, D.A.; Bandyopadhyay, A.; Deshpande, A.; Koul, S.; Kandalkar, S.; Patil, P.; Khose, G.; Vyas, S.; Mone, M.; Bhosale, S.; Singh, U.; De, S.; Meru, A.; Gundu, J.; Chugh, A.; Palle, V.P.; Mookhtiar, K.A.; Vacca, J.P.; Chakravarty, P.K.; Nargund, R.P.; Wright, S.D.; Roy, S.; Graziano, M.P.; Cully, D.; Ca, C.a.i.
Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain L-2-hydroxy acid oxidase
Bioorg. Med. Chem. Lett.
22
4341-4347
2012
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Schmitz, J.; Srikanth, N.V.; Huedig, M.; Poschmann, G.; Lercher, M.J.; Maurino, V.G.
The ancestors of diatoms evolved a unique mitochondrial dehydrogenase to oxidize photorespiratory glycolate
Photosynth. Res.
132
183-196
2017
Phaeodactylum tricornutum (B7FUG8), Phaeodactylum tricornutum
Manually annotated by BRENDA team
Li, X.; Knight, J.; Fargue, S.; Buchalski, B.; Guan, Z.; Inscho, E.W.; Liebow, A.; Fitzgerald, K.; Querbes, W.; Todd Lowther, W.; Holmes, R.P.
Metabolism of (13)C5-hydroxyproline in mouse models of primary hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase
Biochim. Biophys. Acta
1862
233-239
2016
Mus musculus (Q9WU19), Mus musculus, Mus musculus C57BL/6J (Q9WU19)
Manually annotated by BRENDA team
Su, C.; Yu, L.; Yao, T.; Zeng, S.
Cloning and expression of recombinant rat long-chain 2-hydroxy acid oxidase
Chin. Pharmaceut. J.
48
331-336
2013
Rattus norvegicus (Q07523)
-
Manually annotated by BRENDA team
Mattu, S.; Fornari, F.; Quagliata, L.; Perra, A.; Angioni, M.M.; Petrelli, A.; Menegon, S.; Morandi, A.; Chiarugi, P.; Ledda-Columbano, G.M.; Gramantieri, L.; Terracciano, L.; Giordano, S.; Columbano, A.
The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival
J. Hepatol.
64
891-898
2016
Rattus norvegicus (Q07523), Mus musculus (Q9NYQ2), Homo sapiens (Q9NYQ3), Mus musculus C3H (Q9NYQ2), Rattus norvegicus Fischer 344 (Q07523)
Manually annotated by BRENDA team
Cao, Y.; Han, S.; Yu, L.; Qian, H.; Chen, J.Z.
MD and QM/MM studies on long-chain L-alpha-hydroxy acid oxidase substrate binding features and oxidation mechanism
J. Phys. Chem. B
118
5406-5417
2014
Rattus norvegicus (Q07523)
Manually annotated by BRENDA team
Esser, C.; Kuhn, A.; Groth, G.; Lercher, M.J.; Maurino, V.G.
Plant and animal glycolate oxidases have a common eukaryotic ancestor and convergently duplicated to evolve long-chain 2-hydroxy acid oxidases
Mol. Biol. Evol.
31
1089-1101
2014
Arabidopsis thaliana (Q24JJ8), Arabidopsis thaliana (Q9LJH5), Arabidopsis thaliana (Q9LRR9)
Manually annotated by BRENDA team
Dutta, C.; Avitahl-Curtis, N.; Pursell, N.; Larsson Cohen, M.; Holmes, B.; Diwanji, R.; Zhou, W.; Apponi, L.; Koser, M.; Ying, B.; Chen, D.; Shui, X.; Saxena, U.; Cyr, W.A.; Shah, A.; Nazef, N.; Wang, W.; Abrams, M.; Dudek, H.; Salido, E.; Brown, B.D.; Lai, C.
Inhibition of glycolate oxidase with dicer-substrate siRNA reduces calcium oxalate deposition in a mouse model of primary hyperoxaluria type 1
Mol. Ther.
24
770-778
2016
Mus musculus (Q9WU19), Mus musculus, Mus musculus C57BL/6 (Q9WU19)
Manually annotated by BRENDA team
Satomura, T.; Hayashi, J.; Sakamoto, H.; Nunoura, T.; Takaki, Y.; Takai, K.; Takami, H.; Ohshima, T.; Sakuraba, H.; Suye, S.I.
D-Lactate electrochemical biosensor prepared by immobilization of thermostabledye-linked D-lactate dehydrogenase from Candidatus Caldiarchaeum subterraneum
J. Biosci. Bioeng.
126
425-430
2018
Candidatus Caldarchaeum subterraneum (E6N788)
Manually annotated by BRENDA team
Liu, Y.; Wu, W.; Chen, Z.
Structures of glycolate oxidase from Nicotiana benthamiana reveal a conserved pH sensor affecting the binding of FMN
Biochem. Biophys. Res. Commun.
503
3050-3056
2018
Nicotiana benthamiana (E1AXT8), Nicotiana benthamiana
Manually annotated by BRENDA team
Zhang, Z.; Li, X.; Cui, L.; Meng, S.; Ye, N.; Peng, X.
Catalytic and functional aspects of different isozymes of glycolate oxidase in rice
BMC Plant Biol.
17
135
2017
Oryza sativa Japonica Group (Q10CE4), Oryza sativa Japonica Group (Q7FAS1), Oryza sativa Japonica Group (Q8H3I4)
Manually annotated by BRENDA team
Matsumura, K.; Yamada, M.; Yamashita, T.; Muto, H.; Nishiyama, K.I.; Shimoi, H.; Isobe, K.
Expression of alcohol oxidase gene from Ochrobactrum sp. AIU 033 in recombinant Escherichia coli through the twin-arginine translocation pathway
J. Biosci. Bioeng.
128
13-21
2019
Ochrobactrum sp. AIU 033
Manually annotated by BRENDA team
Li, D.; Han, Q.; Zhang, T.
Cloning and coexpression of recombinant N-demethylase B and glycolate oxidase genes in Escherichia coli
Mol. Biol. Rep.
46
505-510
2019
Spinacia oleracea (P05414), Spinacia oleracea
Manually annotated by BRENDA team
Yang, M.; Li, Z.; Zhang, K.; Zhang, X.; Zhang, Y.; Wang, X.; Han, C.; Yu, J.; Xu, K.; Li, D.
Barley stripe mosaic virus gammab interacts with glycolate oxidase and inhibits peroxisomal ROS production to facilitate virus infection
Mol. Plant
11
338-341
2018
Nicotiana benthamiana (E1AXT8)
Manually annotated by BRENDA team
Zabaleta, N.; Barberia, M.; Martin-Higueras, C.; Zapata-Linares, N.; Betancor, I.; Rodriguez, S.; Martinez-Turrillas, R.; Torella, L.; Vales, A.; Olaguee, C.; Vilas-Zornoza, A.; Castro-Labrador, L.; Lara-Astiaso, D.; Prosper, F.; Salido, E.; Gonzalez-Aseguinolaza, G.; Rodriguez-Madoz, J.R.
CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I
Nat. Commun.
9
5454
2018
Mus musculus (Q9WU19)
Manually annotated by BRENDA team
Ahammed, G.J.; Li, X.; Zhang, G.; Zhang, H.; Shi, J.; Pan, C.; Yu, J.; Shi, K.
Tomato photorespiratory glycolate-oxidase-derived H2O2 production contributes to basal defence against Pseudomonas syringae
Plant Cell Environ.
41
1126-1138
2018
Solanum lycopersicum
Manually annotated by BRENDA team
Schmitz, J.; Huedig, M.; Meier, D.; Linka, N.; Maurino, V.G.
The genome of Ricinus communis encodes a single glycolate oxidase with different functions in photosynthetic and heterotrophic organs
Planta
252
100
2020
Ricinus communis (B9S0Y9), Ricinus communis (B9ST74), Ricinus communis
Manually annotated by BRENDA team
Xu, Y.P.; Yang, J.; Cai, X.Z.
Glycolate oxidase gene family in Nicotiana benthamiana genome-wide identification and functional analyses in disease resistance
Sci. Rep.
8
8615
2018
Nicotiana benthamiana
Manually annotated by BRENDA team