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1.1.3.15: (S)-2-hydroxy-acid oxidase

This is an abbreviated version!
For detailed information about (S)-2-hydroxy-acid oxidase, go to the full flat file.

Word Map on EC 1.1.3.15

Reaction

an (S)-2-hydroxy carboxylate
+
O2
=
a 2-oxo carboxylate
+
H2O2

Synonyms

(L)-2-HAOX, (S)-2-hydroxy-acid oxidase, peroxisomal, 2-hydroxy acid oxidase, CSUB_C1080, EC 1.1.3.1, GLO, Glo1, GLO3, Glo4, glycolate oxidase, GO, GO1, GOX, GOX1, GOX2, HAO1, Hao2, HAOX, HAOX1, HAOX2, HAOX3, hydroxy-acid oxidase A, hydroxy-acid oxidase B, hydroxyacid oxidase 1, hydroxyacid oxidase A, L-2-hydroxy acid oxidase, L-2-hydroxyacid oxidase A, L-alpha-hydroxy acid oxidase, L-amino acid oxidase, L-LAC-OX, L-lactate monooxygenase, L-lactate oxidase, L-LOx, lactate oxidase, LCHAO, LctO, lHAOX1, lHAOX2, long chain hydroxy acid oxidase, long chain l-2-hydroxy acid oxidase, long chain L-2-hydroxy acid oxidase 2, long-chain 2-hydroxy acid oxidase, long-chain L-alpha-hydroxy acid oxidase, LOX, More, NbS00005125g0015, NbS00060838g0004, Nbv5tr6245008, Os03g0786100, Os04g0623500, Os07g0616500, oxidase, L-2-hydroxy acid, RCOM_0631490, RCOM_0684800

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.15 (S)-2-hydroxy-acid oxidase

KM Value

KM Value on EC 1.1.3.15 - (S)-2-hydroxy-acid oxidase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0052 - 103
(S)-lactate
0.033
2,6-dichlorophenolindophenol
-
-
0.045
2-Hydroxyoctanoate
-
isoenzyme HAOX3
0.75
2-mercaptoethanol-glyoxylate adduct
-
-
0.04
2-oxo-octanoate
-
4.4
Bromopyruvate
-
transhydrogenation reaction
2.2
coenzyme A-glyoxylate adduct
-
-
0.28
dichlorophenolindophenol
-
cosubstrate: glycolate
4
DL-2-hydroxy-3-butynoate
-
-
0.38
DL-2-hydroxy-3-heptynoate
-
-
7
DL-2-hydroxy-3-hexynoate
-
-
0.14
DL-2-hydroxy-3-octynoate
-
-
9
DL-2-hydroxy-3-pentynoate
-
-
0.7 - 1.1
DL-2-hydroxy-4-methylthiobutanoic acid
0.6 - 14
DL-2-hydroxybutyrate
0.15 - 3.2
DL-2-hydroxycaproate
0.6
DL-2-hydroxyisocaproate
-
-
0.6 - 8
DL-2-hydroxyisovalerate
0.25 - 13
DL-2-hydroxyvalerate
0.7 - 28
DL-3-chlorolactate
18 - 27
DL-alpha-hydroxy-n-butyrate
5.5 - 10
DL-alpha-hydroxy-n-valerate
71
DL-alpha-phenyllactate
-
-
5 - 53
DL-glycerate
27
DL-lactate
-
-
4
DL-methionine
-
pH 7.5
0.1
DL-phenyllactate
-
pH 7.0 and 7.5
10
DL-vinylglycolate
-
-
2.76 - 7.14
glycerate
0.0056 - 2.1
glycolate
1.41 - 6.51
glyoxylate
0.046
L-2-hydroxy octanoate
-
1.36
L-2-hydroxy palmitate
-
1.82
L-2-hydroxy-4-methylthiobutanoic acid
-
-
2.4
L-2-hydroxy-beta-methylvalerate
-
long chain oxidase
0.3 - 2.5
L-2-Hydroxyisocaproate
140
L-alpha-hydroxy-beta-methylvalerate
-
A95G mutant
125
L-alpha-hydroxy-isovalerate
-
A95G mutant
1.9
L-alpha-hydroxyphenyllactate
-
-
2.2
L-beta-Phenyllactate
-
long chain oxidase
0.34 - 16.5
L-lactate
5.3 - 15
L-leucine
90
L-lysine
-
-
0.16 - 20
L-Mandelate
53
L-methionine
-
-
0.09 - 0.13
L-Phenyllactate
35 - 40
L-tryptophan
0.4
N-acetylcysteamine-glyoxylate adduct
-
-
0.022 - 0.64
O2
0.7
pantetheine-glyoxylate adduct
-
-
0.03
propane-1,3-dithiol-glyoxylate adduct
-
-
additional information
additional information
-