1.1.1.91: aryl-alcohol dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about aryl-alcohol dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

AAD, AAD1, AAD14, Aad14p, Aad1p, AAD4, Aad4p, ADH, aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate) coniferyl alcohol dehydrogenase, aryl-alcohol dehydrogenase, coniferyl alcohol dehydrogenase, NADPH-linked benzaldehyde reductase, PcAad1p, ScAad14p protein, ScAad4p protein, SDR A5, SDR B3, short-chain dehydrogenase/reductase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.91 aryl-alcohol dehydrogenase (NADP+)

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Results	in table
3	Activating Compound
454	AA Sequence
1	CAS Registry Number
7	Cloned(Commentary)
27	Cofactor
1	Crystallization (Commentary)
3	Expression
14	General Information
41	Inhibitors
37	kcat/KM [mM/s]
8	Ki Value [mM]
72	KM Value [mM]
4	Metals/Ions
10	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
74	Organism
14	pH Optimum
7	pH Range
10	Protein Variants
10	Purification (Commentary)
1	Reaction
3	Reaction Type
32	Reference
15	Source Tissue
7	Specific Activity [micromol/min/mg]
4	Storage Stability
143	Substrates and Products (Substrate)
7	Subunits
42	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
3	Temperature Range [°C]
2	Temperature Stability [°C]
45	Turnover Number [1/s]

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0047

(R)-1-phenylethanol

Ralstonia sp.

C0IR58

wild-type, pH 8.3, 30°C

737897

0.0115 - 0.783

(S)-1-phenylethanol

4 entries

4.3 - 13.7

(S)-2-octanol

2 entries

2.37 - 8.833

3,4-dimethoxybenzaldehyde

3 entries

2.55

3,4-dimethoxybenzyl alcohol

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

9.83

3,5-dimethoxybenzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

3.83

3-hydroxy-4-methoxy-benzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

3.33

4-Hydroxy-3-methoxy-benzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

4.33

4-hydroxy-3-methoxy-benzyl alcohol

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

8.16

4-methoxybenzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

0.37

4-nitrobenzaldehyde

Saccharomyces cerevisiae

P42884, Q07747

pH 6.1, temperature not specified in the publication

762641

2.93

5-(hydroxymethyl)-2-furaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

7.16 - 360

benzaldehyde

3 entries

93.3

benzyl alcohol

Yokenella sp. WZY002

W6CX26

at pH 6.5 and 65°C

735498

11.17

cinnamaldehyde

Phanerodontia chrysosporium

-

pH 6.1, temperature not specified in the publication

762641

405

crotonaldehyde

Yokenella sp. WZY002

W6CX26

at pH 8.0 and 55°C

735498

101

crotonyl alcohol

Yokenella sp. WZY002

W6CX26

at pH 8.0 and 55°C

735498

0.77 - 2.3

Heptanal

3 entries

0.83 - 4.12

hexanal

3 entries

0.022 - 0.08

NAD+

4 entries

2

NADH

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

0.00003 - 433

NADP+

6 entries

11.33

NADPH

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

11.16

phenylacetaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

11.16

trans-cinnamaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

0.0115

(S)-1-phenylethanol

Ralstonia sp.

C0IR58

wild-type, pH 8.3, 30°C

737897

0.023

(S)-1-phenylethanol

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S/A86N/S88A, pH 8.3, 30°C

737897

0.042

(S)-1-phenylethanol

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S, pH 8.3, 30°C

737897

0.783

(S)-1-phenylethanol

Ralstonia sp.

C0IR58

mutant G37D, pH 8.3, 30°C

737897

4.3

(S)-2-octanol

Cupriavidus necator

-

isoform SDR B3, at pH 10.0 and 40°C

738738

13.7

(S)-2-octanol

Cupriavidus necator

-

isoform SDR A5, at pH 10.0 and 40°C

738738

2.37

3,4-dimethoxybenzaldehyde

Saccharomyces cerevisiae

P42884, Q07747

pH 6.1, temperature not specified in the publication

762641

8.83

3,4-dimethoxybenzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, temperature not specified in the publication

762641

8.833

3,4-dimethoxybenzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

7.16

benzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

7.17

benzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, temperature not specified in the publication

762641

360

benzaldehyde

Yokenella sp. WZY002

W6CX26

at pH 6.5 and 65°C

735498

0.77

Heptanal

Saccharomyces cerevisiae

P42884, Q07747

pH 6.1, temperature not specified in the publication

762641

1.07

Heptanal

Saccharomyces cerevisiae

P42884, Q07747

pH 6.1, temperature not specified in the publication

762641

2.3

Heptanal

Phanerodontia chrysosporium

-

pH 6.1, temperature not specified in the publication

762641

0.83

hexanal

Saccharomyces cerevisiae

P42884, Q07747

pH 6.1, temperature not specified in the publication

762641

2.87

hexanal

Saccharomyces cerevisiae

P42884, Q07747

pH 6.1, temperature not specified in the publication

762641

4.12

hexanal

Phanerodontia chrysosporium

-

pH 6.1, temperature not specified in the publication

762641

0.022

NAD+

Ralstonia sp.

C0IR58

wild-type, pH 8.3, 30°C

737897

0.03

NAD+

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S/A86N/S88A, pH 8.3, 30°C

737897

0.038

NAD+

Ralstonia sp.

C0IR58

mutant G37D, pH 8.3, 30°C

737897

0.08

NAD+

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S, pH 8.3, 30°C

737897

0.00003

NADP+

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S, pH 8.3, 30°C

737897

0.0025

NADP+

Ralstonia sp.

C0IR58

mutant G37D, pH 8.3, 30°C

737897

1.65

NADP+

Ralstonia sp.

C0IR58

wild-type, pH 8.3, 30°C

737897

2.56

NADP+

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

194

NADP+

Yokenella sp. WZY002

W6CX26

with crotyl alcohol as cosubstrate, at pH 8.0 and 55°C

735498

433

NADP+

Yokenella sp. WZY002

W6CX26

with crotonaldehyde as cosubstrate, at pH 8.0 and 55°C

735498