1.1.1.91: aryl-alcohol dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about aryl-alcohol dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

AAD, AAD1, AAD14, Aad14p, Aad1p, AAD4, Aad4p, ADH, aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate) coniferyl alcohol dehydrogenase, aryl-alcohol dehydrogenase, coniferyl alcohol dehydrogenase, NADPH-linked benzaldehyde reductase, PcAad1p, ScAad14p protein, ScAad4p protein, SDR A5, SDR B3, short-chain dehydrogenase/reductase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.91 aryl-alcohol dehydrogenase (NADP+)

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Results	in table
3	Activating Compound
454	AA Sequence
1	CAS Registry Number
7	Cloned(Commentary)
27	Cofactor
1	Crystallization (Commentary)
3	Expression
14	General Information
41	Inhibitors
37	kcat/KM [mM/s]
8	Ki Value [mM]
72	KM Value [mM]
4	Metals/Ions
10	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
74	Organism
14	pH Optimum
7	pH Range
10	Protein Variants
10	Purification (Commentary)
1	Reaction
3	Reaction Type
32	Reference
15	Source Tissue
7	Specific Activity [micromol/min/mg]
4	Storage Stability
143	Substrates and Products (Substrate)
7	Subunits
42	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
3	Temperature Range [°C]
2	Temperature Stability [°C]
45	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 1.1.1.91 - aryl-alcohol dehydrogenase (NADP+)

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kcat/KM VALUE [1/mMs^-1]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0047

(R)-1-phenylethanol

Ralstonia sp.

C0IR58

wild-type, pH 8.3, 30°C

737897

0.00115 - 0.65

(S)-1-phenylethanol

4 entries

0.6 - 1.8

(S)-2-octanol

2 entries

733 - 735.8

3,4-dimethoxybenzaldehyde

2 entries

6.8

3,4-dimethoxybenzyl alcohol

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

450

3,5-dimethoxybenzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

2.66

3-hydroxy-4-methoxy-benzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

2.33

4-Hydroxy-3-methoxy-benzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

0.166

4-hydroxy-3-methoxy-benzyl alcohol

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

90

4-methoxybenzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

10

5-(hydroxymethyl)-2-furaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

4.2 - 899

benzaldehyde

3 entries

6.6

benzyl alcohol

Yokenella sp. WZY002

W6CX26

at pH 6.5 and 65°C

735498

3.29

cinnamaldehyde

Phanerodontia chrysosporium

-

pH 6.1, temperature not specified in the publication

762641

122

crotonaldehyde

Yokenella sp. WZY002

W6CX26

at pH 8.0 and 55°C

735498

11

crotonyl alcohol

Yokenella sp. WZY002

W6CX26

at pH 8.0 and 55°C

735498

0.007 - 0.073

NAD+

4 entries

10

NADH

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

0.0001 - 720

NADP+

6 entries

283

NADPH

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

11.16

phenylacetaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

3.33

trans-cinnamaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

0.00115

(S)-1-phenylethanol

Ralstonia sp.

C0IR58

wild-type, pH 8.3, 30°C

737897

0.0013

(S)-1-phenylethanol

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S/A86N/S88A, pH 8.3, 30°C

737897

0.0052

(S)-1-phenylethanol

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S, pH 8.3, 30°C

737897

0.65

(S)-1-phenylethanol

Ralstonia sp.

C0IR58

mutant G37D, pH 8.3, 30°C

737897

0.6

(S)-2-octanol

Cupriavidus necator

-

isoform SDR B3, at pH 10.0 and 40°C

738738

1.8

(S)-2-octanol

Cupriavidus necator

-

isoform SDR A5, at pH 10.0 and 40°C

738738

733

3,4-dimethoxybenzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

735.8

3,4-dimethoxybenzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, temperature not specified in the publication

762641

4.2

benzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, temperature not specified in the publication

762641

5

benzaldehyde

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

899

benzaldehyde

Yokenella sp. WZY002

W6CX26

at pH 6.5 and 65°C

735498

0.007

NAD+

Ralstonia sp.

C0IR58

wild-type, pH 8.3, 30°C

737897

0.0167

NAD+

Ralstonia sp.

C0IR58

mutant G37D, pH 8.3, 30°C

737897

0.038

NAD+

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S/A86N/S88A, pH 8.3, 30°C

737897

0.073

NAD+

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S, pH 8.3, 30°C

737897

0.0001

NADP+

Ralstonia sp.

C0IR58

mutant N15G/G37D/R38V/R39S, pH 8.3, 30°C

737897

0.0011

NADP+

Ralstonia sp.

C0IR58

mutant G37D, pH 8.3, 30°C

737897

32.33

NADP+

Ralstonia sp.

C0IR58

wild-type, pH 8.3, 30°C

737897

68

NADP+

Phanerodontia chrysosporium

-

pH 6.1, 30°C

724669

278

NADP+

Yokenella sp. WZY002

W6CX26

with crotyl alcohol as cosubstrate, at pH 8.0 and 55°C

735498

720

NADP+

Yokenella sp. WZY002

W6CX26

with crotonaldehyde as cosubstrate, at pH 8.0 and 55°C

735498