1.1.1.80: isopropanol dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about isopropanol dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

ADH, IDH, isopropanol dehydrogenase, NADP-dependent isopropanol dehydrogenase, NADPH-dependent primary-secondary alcohol dehydrogenase, S-ADH, TBADH, TVAG_228780

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.80 isopropanol dehydrogenase (NADP+)

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Results	in table
158	AA Sequence
3	Application
1	CAS Registry Number
2	Cloned(Commentary)
8	Cofactor
1	Expression
3	General Information
1	General Stability
6	Inhibitors
2	kcat/KM [mM/s]
19	KM Value [mM]
3	Localization
2	Metals/Ions
4	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
11	Organic Solvent Stability
18	Organism
8	Pathway
24	PDB ID
8	pH Optimum
1	pH Range
2	pH Stability
1	Protein Variants
2	Purification (Commentary)
1	Reaction
3	Reaction Type
8	Reference
1	Source Tissue
38	Substrates and Products (Substrate)
1	Subunits
13	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
2	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.1.1.80 - isopropanol dehydrogenase (NADP+)

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

butan-2-ol + NADP+

butanone + NADPH + H+

Trichomonas vaginalis

A2DJ40

preferred direction of the reaction is reduction rather than oxidation

724969

-

-

r

propan-2-ol + NADP+

acetone + NADPH + H+

Trichomonas vaginalis

A2DJ40

preferred direction of the reaction is reduction rather than oxidation

724969

-

-

r

additional information

?

-

Rattus norvegicus

-

possibly takes part in the further metabolic reactions of the fragments formed from the side-chain of the steroid hormone precursor in the adrenals or gonads

287362

-

-

?