1.1.1.8: glycerol-3-phosphate dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about glycerol-3-phosphate dehydrogenase (NAD+), go to the full flat file.

Reaction

Synonyms

(NAD+)-dependent G3pdh, (NAD+)-dependent glycerol-3-phosphate dehydrogenase, 100383152, alpha glycerophosphate dehydrogenase, alpha-glycerol phosphate dehydrogenase (NAD), alpha-glycerophosphate dehydrogenase (NAD), Cagpd1, Cagpd1p, Cagpd2, Cagpd2p, cG3PDH, CgGPD, cGPdH, cytoplasmic NAD-dependent glycerol-3-phosphate dehydrogenase, cytosolic GPDH, dehydrogenase, glycerol phosphate, DhGPD1, G-3-P dehydrogenase, G3P dehydrogenase, G3PD, G3PD1, G3PD2, G3PD3, G3PDH, GDM, GDP2, GLPD, GLY1, glycerol 1-phosphate dehydrogenase, glycerol 3-phosphate dehydrogenase, glycerol 3-phosphate dehydrogenase 1, glycerol phosphate dehydrogenase (NAD), glycerol-3-phosphate dehydrogenase, glycerol-3-phosphate dehydrogenase 1, glycerophosphate dehydrogenase (NAD), GPD, GPD1, Gpd1p, gpd2p, GPDH, GPDH-1, GPDH-2, GPDH1, GPDH2, GPDH3, GPDH4, GPDH5, GPDH: NAD+ 2 oxidoreductase, GPDH: NAD+ 2 oxidorreductase, GPDHc1, GRMZM2G090747_T01, GRMZM2G155348_T01, GRMZM2G173195_T01, GRMZM6G161711_T01, hydroglycerophosphate dehydrogenase, L-alpha-glycerol phosphate dehydrogenase, L-alpha-glycerophosphate dehydrogenase, L-glycerol 3-phosphate dehydrogenase, L-glycerol phosphate dehydrogenase, L-glycerophosphate dehydrogenase, mGPDH, NAD+-dependent G3P dehydrogenase, NAD+-dependent glycerol 3-phosphate dehydrogenase, NAD+-dependent glycerol-3-phosphate dehydrogenase, NAD+-GPDH, NAD-alpha-glycerophosphate dehydrogenase, NAD-dependent cG3PDH, NAD-dependent glycerol phosphate dehydrogenase, NAD-dependent glycerol-3-phosphate dehydrogenase, NAD-L-glycerol-3-phosphate dehydrogenase, NAD-linked glycerol 3-phosphate dehydrogenase, NADH-dihydroxyacetone phosphate reductase, NADP+-dependent glycerol 3-phosphate dehydrogenase, SFD1, SFD1/GLY1, ZEAMMB73_Zm00001d010670, ZEAMMB73_Zm00001d041962, ZEAMMB73_Zm00001d042152, ZmGPDH1, ZmGPDH3, ZmGPDH4, ZmGPDH5

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+)

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Results	in table
18	Activating Compound
7732	AA Sequence
16	Application
1	CAS Registry Number
28	Cloned(Commentary)
138	Cofactor
9	Crystallization (Commentary)
213	Disease/ Diagnostics
20	Expression
50	General Information
31	General Stability
14	IC50 Value
123	Inhibitors
16	kcat/KM [mM/s]
3	Ki Value [mM]
160	KM Value [mM]
51	Localization
4	Metals/Ions
59	Molecular Weight [Da]
83	Natural Substrates/ Products (Substrates)
399	Organism
5	Pathway
32	PDB ID
33	pH Optimum
18	pH Range
13	pH Stability
6	pI Value
2	Posttranslational Modification
12	Protein Variants
47	Purification (Commentary)
12	Reaction
3	Reaction Type
141	Reference
129	Source Tissue
47	Specific Activity [micromol/min/mg]
22	Storage Stability
166	Substrates and Products (Substrate)
50	Subunits
207	Synonyms
1	Systematic Name
15	Temperature Optimum [°C]
28	Temperature Stability [°C]
15	Turnover Number [1/s]

Metals Ions

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Metals Ions on EC 1.1.1.8 - glycerol-3-phosphate dehydrogenase (NAD+)

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METALS and IONS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

KCl

Debaryomyces hansenii

-

0.1-0.3 M, chloride salts become strongly inhibitory at higher concentrations, replacing K+ with Na+ or NH4+yields similar results

287353

MgCl2

Debaryomyces hansenii

-

0.1-0.3 M

287353

MgSO4

Debaryomyces hansenii

-

0.1-0.3 M, slight activation at low ionic strength, most inhibitory at higher concentration

287353

NaCl

Dunaliella salina

-

when Dunaliella salina is cultured chronically at various salinities, the accumulation of single cell glycerol increases with increased salinity, Dunaliella salina also can rapidly decrease or increase single cell glycerol contents to adapt to hypoosmotic or hyperosmotic shock

723769