1.1.1.62: 17beta-estradiol 17-dehydrogenase

This is an abbreviated version!
For detailed information about 17beta-estradiol 17-dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.62

1.1.1.62

progesterone

estrone

androgen

testosterone

17beta-hsds

ovarian

aromatase

steroidogenic

endometrium

androstenedione

aldo-keto

steroidogenesis

progestin

granulosa

luteal

akr1c2

alpha-hsd

sulfatase

medicine

alpha-dihydroprogesterone

corpora

pregnenolone

d-bifunctional

endometriotic

hsd17b3

3beta-hydroxysteroid

luteolysis

cyp19a1

alpha-hydroxyprogesterone

vlcfas

cochliobolus

17-ketosteroids

hsd3b2

3alpha-hydroxysteroid

sult1e1

5alpha-reductase

srd5a1

5alpha-dihydrotestosterone

lunatus

3betahsd

p450arom

alpha-diol

17-keto

c19-steroids

diagnostics

drug development

Reaction

Synonyms

(17beta-HSD) type 1, (17beta-HSD) type 2, 17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 12, 17-beta-hydroxysteroid dehydrogenase type 2, 17-HOR, 17-HSD, 17beta HSD1, 17beta,20alpha-hydroxysteroid dehydrogenase, 17beta-estradiol dehydrogenase, 17beta-HSD, 17beta-hsd 14, 17beta-HSD I, 17beta-HSD type 1, 17beta-HSD type 12, 17beta-HSD type 2, 17beta-HSD type 4, 17beta-HSD type 5, 17beta-HSD type 7, 17beta-HSD type 8, 17beta-HSD1, 17beta-HSD10, 17beta-HSD12, 17beta-HSD14, 17beta-HSD2, 17beta-HSD4, 17beta-HSD5, 17beta-HSD7, 17beta-HSD7 2, 17beta-HSDcl, 17beta-hydroxysteroid dehydrogenase, 17beta-hydroxysteroid dehydrogenase 1, 17beta-hydroxysteroid dehydrogenase 2, 17beta-hydroxysteroid dehydrogenase 4, 17beta-hydroxysteroid dehydrogenase type 1, 17beta-hydroxysteroid dehydrogenase type 10, 17beta-hydroxysteroid dehydrogenase type 12, 17beta-hydroxysteroid dehydrogenase type 14, 17beta-hydroxysteroid dehydrogenase type 2, 17beta-hydroxysteroid dehydrogenase type 4, 17beta-hydroxysteroid dehydrogenase type 5, 17beta-hydroxysteroid dehydrogenase type 6, 17beta-hydroxysteroid dehydrogenase type 7, 17beta-hydroxysteroid dehydrogenase type 8, 17beta-hydroxysteroid dehydrogenase type I, 17beta-hydroxysteroid dehydrogenase type IV, 17beta-hydroxysteroid dehydrogenase types 1, 17beta-hydroxysteroid dehydrogenases type 1, 17betaHSD, 17betaHSD1, 17betaHSD14, 17betaHSD6, 17HSD1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, 20alpha-hydroxysteroid dehydrogenase, 3beta-HSD, 3beta-hydroxysteroid dehydrogenase, 3betaHSD, 7beta-HSD type 1, 7beta-HSD7, AKR1B15, AKR1C1, AKR1C2, AKR1C3, AKR1C4, aldo-keto reductase 1B15, C6Y55_RS00895, C6Y55_RS01070, C6Y55_RS01190, C6Y55_RS15130, dehydrogenase, estradiol 17beta-, E2DH, EDH, estradiol 17beta-dehydrogenase, estradiol dehydrogenase, estrogen 17-oxidoreductase, estrogenic 17beta-hydroxysteroid dehydrogenase, form 2 type 7 17beta-hydroxysteroid dehydrogenase, HSD17B1, HSD17B12, HSD17B2, HSD17B4, HSD17B7, hydroxysteroid (17-beta) dehydrogenase 1, Ke6 protein, mf17beta-HSD12, microsomal 17-beta-hydroxysteroid dehydrogenase, More, NlHsd17b12, oestradiol-17beta hydroxysteroid dehydrogenase, placental 17-beta-hydroxysteroid dehydrogenase, PRAP, PRL receptor associated protein, reductive 17beta-hydroxysteroid dehydrogenase type 7, testicular 17-beta-hydroxysteroid dehydrogenase, type 1 17beta-HSD, type 1 17beta-hydroxysteroid dehydrogenase, type 12 17beta-HSD, type 12 17beta-hydroxysteroid dehydrogenase, type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase, type 5 17-hydroxysteroid dehydrogenase/prostaglandin F synthase, type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase, type 7 17beta-hydroxysteroid dehydrogenase, type 8 17beta-HSD, type 8 17beta-hydroxysteroid dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.62 17beta-estradiol 17-dehydrogenase

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Results	in table
5	Activating Compound
556	AA Sequence
27	Application
1	CAS Registry Number
42	Cloned(Commentary)
152	Cofactor
14	Crystallization (Commentary)
814	Disease/ Diagnostics
28	Expression
43	General Information
284	IC50 Value
737	Inhibitors
9	kcat/KM [mM/s]
42	Ki Value [mM]
97	KM Value [mM]
33	Localization
2	Metals/Ions
19	Molecular Weight [Da]
80	Natural Substrates/ Products (Substrates)
167	Organism
3	Pathway
112	PDB ID
23	pH Optimum
5	pH Range
1	pI Value
3	Posttranslational Modification
25	Protein Variants
24	Purification (Commentary)
9	Reaction
3	Reaction Type
161	Reference
370	Source Tissue
10	Specific Activity [micromol/min/mg]
4	Storage Stability
342	Substrates and Products (Substrate)
16	Subunits
256	Synonyms
1	Systematic Name
17	Temperature Optimum [°C]
2	Temperature Range [°C]
3	Temperature Stability [°C]
44	Turnover Number [1/s]

KI Value

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KI Value on EC 1.1.1.62 - 17beta-estradiol 17-dehydrogenase

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0.0041

(6aS)-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydronaphtho[2',1':4,5]indeno[1,2-c]pyrazol-2-ol