1.1.1.48: D-galactose 1-dehydrogenase

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For detailed information about D-galactose 1-dehydrogenase, go to the full flat file.

Reaction

Synonyms

beta-galactose dehydrogenase, D-galactose dehydrogenase, D-galactose: NAD+ 1-oxidoreductase, D-galactose:NAD+ oxidoreductase, GADH, GALDH, NAD-dependent D-galactose dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.48 D-galactose 1-dehydrogenase

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Results	in table
316	AA Sequence
5	Application
1	CAS Registry Number
6	Cloned(Commentary)
4	Cofactor
1	Expression
4	Inhibitors
29	KM Value [mM]
4	Localization
8	Molecular Weight [Da]
40	Natural Substrates/ Products (Substrates)
40	Organism
4	Oxidation Stability
3	Pathway
15	PDB ID
8	pH Optimum
1	pH Stability
7	Purification (Commentary)
9	Reaction
1	Reaction Type
37	Reference
1	Source Tissue
28	Specific Activity [micromol/min/mg]
3	Storage Stability
65	Substrates and Products (Substrate)
7	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
4	Temperature Stability [°C]
2	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.1.1.48 - D-galactose 1-dehydrogenase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

5,5'-dithiobis(2-nitrobenzoic acid)

Pelomonas saccharophila

-

reacts with first 4 sulfhydryl groups of enzyme, inhibition is completely reversible upon addition of reducing agents, NAD+ and NADH protect against inactivation

286972

anthraquinone-diamino-benzosulfonyl-dichlorotriazine

Pseudomonas fluorescens

-

i.e. Vilmafix Blue A-R, and other derivatives of longer side chain length, inactivation, overview

655445

NaCl

Pseudomonas fluorescens

-

almost no activity at 10% (w/v)

741360

p-chloromercuribenzoate

Pelomonas saccharophila

-

-

286972