1.1.1.47: glucose 1-dehydrogenase [NAD(P)+]
This is an abbreviated version!
For detailed information about glucose 1-dehydrogenase [NAD(P)+], go to the full flat file.
Word Map on EC 1.1.1.47
Reaction
Synonyms
alkali-resistant glucose 1-dehydrogenase, beta-D-glucose:NAD(P)+ 1-oxido-reductase, beta-D-glucose:NAD(P)+ 1-oxidoreductase, BmGlcDH-III, BmGlcDH-IV, bzgdh, D-glucose dehydrogenase (NAD(P)), EC 1.1.5.2, GDH, gdh-2, GDHB, general stress protein 74, GlcDH, GlcDH-I, GlcDH-II, GlcDH-IWG3, glucose 1-dehydrogenase, glucose 1-dehydrogenase 3, glucose 1-dehydrogenase B, glucose 1-dehydrogenase III, glucose 1-dehydrogenase IV, glucose dehydrogenase, glucose1-dehydrogenase, GluDH, GSP74, hexose phosphate dehydrogenase, hexose-6-phosphate dehydrogenase, LsGDH, More, NAD(P)-dependent glucose 1-dehydrogenase, NAD(P)-dependent glucose dehydrogenase, NAD(P)-dependent glucose-1-dehydrogenase, NAD-GDH, nicotinamide adenine dinucleotide (NAD)-linked glucose dehydrogenase, SsGDH, SSO3204
ECTree
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]Advanced search results
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results (Substrates Products
Substrates Products on EC 1.1.1.47 - glucose 1-dehydrogenase [NAD(P)+]
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-amino-2-deoxy-D-glucose + NADP+
2-amino-2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
5% of the activity with D-glucose and NAD+
-
-
?
2-deoxy-beta-D-xylose + NAD+
2-deoxy-D-xylono-1,5-lactone + NADH + H+
-
-
-
-
r
2-deoxy-D-glucose 6-phosphate + NAD+
2-deoxy-D-glucono-1,5-lactone 6-phosphate + NADH
-
-
-
-
?
2-deoxy-D-glucose 6-phosphate + NADP+
2-deoxy-D-glucono-1,5-lactone 6-phosphate + NADPH
-
-
-
-
?
6-deoxy-D-glucose + NAD+
6-deoxy-D-glucono-1,5-lactone + NADH + H+
-
66% of the activity with D-glucose
-
-
?
6-deoxy-D-glucose + NADP+
? + NADPH
-
9% of the activity with D-glucose and NAD+
-
-
?
beta-D-galactose + NADP+
D-galactono-1,5-lactone + NADPH + H+
-
-
-
-
?
beta-D-glucose + NAD(P)(+)
D-glucono-1,5-lactone + NAD(P)H
the enzyme might represent the major player in glucose catabolism via the branched Entner-Doudoroff pathway
-
-
ir
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH
the enzyme is absolutely specific for glucose. D-Galactose, D-allose, D-mannose, D-xylose, L-arabinose, D-ribose, D-xylose, D-arabinose, L-xylose, D-glucosamine, 2-deoxy-D-glucose, D-fucose, D-lactose, D-maltose, D-fructose and ethanol are not used as substrates. the catalytic efficiency for the reaction with beta-D-glucose and NADP+ (kcat/Km) is 7.8 fold higher compared to catalytic efficiency for the reaction with beta-D-glucose and NAD+
-
-
ir
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH
the enzyme is absolutely specific for glucose. D-Galactose, D-allose, D-mannose, D-xylose, L-arabinose, D-ribose, D-xylose, D-arabinose, L-xylose, D-glucosamine, 2-deoxy-D-glucose, D-fucose, D-lactose, D-maltose, D-fructose and ethanol are not used as substrates. the catalytic efficiency for the reaction with beta-D-glucose and NADP+ (kcat/Km) is 7.8 fold higher compared to catalytic efficiency for the reaction with beta-D-glucose and NAD+
-
-
ir
beta-D-glucose 6-phosphate + NAD+
D-glucono-1,5-lactone 6-phosphate + NADPH
-
-
-
-
?
beta-D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
-
26% activity compared to D-glucose
-
-
r
D-allose + NAD+
D-allono-1,5-lactone + NADH
-
8% of the activity with D-glucose
-
-
?
D-allose + NADP+
D-allono-1,5-lactone + NADPH
-
13% of the activity with D-glucose and NAD+
-
-
?
D-altrose + NAD+
D-altrono-1,5-lactone + NADH
-
5% of the activity with D-glucose
-
-
?
D-altrose + NADP+
D-altrono-1,5-lactone + NADPH
-
12% of the activity with D-glucose and NAD+
-
-
?
D-fructose + NAD(P)+
? + NAD(P)H
-
no activity with mutants Q252L and Q252L/E170K
-
-
?
D-fructose + NADP+
?
-
0.03% activity compared to D-glucose
-
-
?
D-galactose + NADP+
?
-
1.09% activity compared to D-glucose
-
-
?
D-galactose 6-phosphate + NAD+
6-phospho-D-galactono-1,5-lactone + NADH + H+
-
-
-
-
r
D-galactose 6-phosphate + NADP+
6-phospho-D-galactono-1,5-lactone + NADPH + H+
-
-
-
-
r
D-glucose + 1-(3-phenylpropyl)-1,4-dihydropyridine-3-carboxamide
D-glucono-1,5-lactone + reduced 1-(3-phenylpropyl)-1,4-dihydropyridine-3-carboxamide
-
-
-
?
D-glucose + 1-benzyl-3-carbamoylpyridin-1-ium chloride
D-glucono-1,5-lactone + reduced 1-benzyl-3-carbamoylpyridin-1-ium chloride
-
-
-
?
D-glucose + 1-phenethyl-1,4-dihydropyridine-3-carboxamide
D-glucono-1,5-lactone + reduced 1-phenethyl-1,4-dihydropyridine-3-carboxamide
-
-
-
?
D-gulose + NAD+
D-gulono-1,5-lactone + NADH
-
8% of the activity with D-glucose
-
-
?
D-gulose + NADP+
D-gulono-1,5-lactone + NADPH
-
12% of the activity with D-glucose and NAD+
-
-
?
D-idose + NAD+
D-idono-1,5-lactone + NADH
-
65% of the activity with D-glucose
-
-
?
D-idose + NADP+
D-idono-1,5-lactone + NADPH
-
12% of the activity with D-glucose and NAD+
-
-
?
D-lactose + NAD+
D-lactono-1,5-lactone + NADH + H+
relative activity: 4.2%
-
-
?
D-lactose + NADP+
?
-
3.0% activity compared to D-glucose
-
-
?
D-maltose + NADP+
?
-
1.03% activity compared to D-glucose
-
-
?
D-mannose + NADP+
?
-
11.53% activity compared to D-glucose
-
-
?
D-ribose + NADP+
D-ribono-1,5-lactone + NADPH
-
4% of the activity with D-glucose and NADP+
-
-
?
D-xylose + NADP+
?
-
12.89% activity compared to D-glucose
-
-
?
2-amino-2-deoxy-D-glucose + NAD+
2-amino-2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
14% of the activity with D-glucose
-
-
?
2-amino-2-deoxy-D-glucose + NAD+
2-amino-2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
26% of the activity with D-glucose
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
113% of the activity with D-glucose
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
Bacillus sp. (in: Bacteria) BG 1722
-
113% of the activity with D-glucose
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
108% of the activity with D-glucose
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
-
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
-
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
-
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
114% of the activity with D-glucose
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
112% relative activity
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
Priestia megaterium M1286
-
112% relative activity
-
-
?
2-deoxy-D-glucose + NAD+
2-deoxy-D-glucono-1,5-lactone + NADH + H+
-
12% of the activity with glucose
-
-
?
2-deoxy-D-glucose + NADP+
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
103% of the activity with D-glucose and NAD+
-
-
?
2-deoxy-D-glucose + NADP+
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
Bacillus sp. (in: Bacteria) BG 1722
-
103% of the activity with D-glucose and NAD+
-
-
?
2-deoxy-D-glucose + NADP+
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
2-deoxy-D-glucose + NADP+
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
2-deoxy-D-glucose + NADP+
2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
25% of the activity with D-glucose and NAD+
-
-
?
beta-D-galactose + NAD+
D-galactono-1,5-lactone + NADH
6.8% of the activity as compared to D-glucose
-
-
?
beta-D-galactose + NAD+
D-galactono-1,5-lactone + NADH
6.8% of the activity as compared to D-glucose
-
-
?
beta-D-galactose + NADP+
D-galactono-1,5-lactone + NADPH
-
-
-
-
?
beta-D-galactose + NADP+
D-galactono-1,5-lactone + NADPH
-
-
-
?
beta-D-galactose + NADP+
D-galactono-1,5-lactone + NADPH
-
low activity
-
-
?
beta-D-glucose + 2,6-dichlorophenol-indophenol
?
-
-
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
enzyme plays a role in germination
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
enzyme plays a role in germination
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
multifunctional enzyme is involved in several catabolic sugar pathways in the endoplasmic reticulum
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
-
-
ir
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
-
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
-
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
best substrate, wild-type and mutant enzymes
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
-
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
-
-
ir
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
first step of the non-phosphorylative Entner-Doudoroff pathway
-
-
ir
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
-
-
-
?
beta-D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H + H+
-
-
-
-
?
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
-
-
-
?
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
velocities of the reverse reaction at pH 7.0 and 8.0 are 2.2% and 5.9% respectively, of the oxidative reaction
-
-
r
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
5.9% velocity for reverse reaction compared to forward reaction at pH 8.0
-
-
r
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
velocities of the reverse reaction at pH 7.0 and 8.0 are 2.2% and 5.9% respectively, of the oxidative reaction
-
-
r
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
5.9% velocity for reverse reaction compared to forward reaction at pH 8.0
-
-
r
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
about 3times more active with NADP+ than with NAD+
-
-
?
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
about 3times more active with NADP+ than with NAD+
-
-
?
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
-
-
-
?
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
although they can utilize both NAD+ and NADP+: GlcDH-III and GlcDH-IV prefer NAD+, and GlcDH-I and GlcDH-II prefer NADP+
-
-
?
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
the enzyme is highly specific for beta-D-glucose
-
-
?
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
9% of the activity with NAD+
-
-
?
beta-D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
GDH-2 is absolutely specific for D-glucose. D-galactose, D-allose, D-mannose, D-xylose, L-arabinose, D-ribose, D-xylose, D-arabinose, L-xylose, D-glucosamine, 2-deoxy-D-glucose, D-fucose, D-lactose, D-maltose, D-fructose and ethanol were not used as substrates. kcat/Km for glucose in the reaction with NAD+ is about 8fold lower compared to kcat/Km of glucose in the reaction with NADP+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
93% of the activity with NAD+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
Bacillus sp. (in: Bacteria) BG 1722
-
93% of the activity with NAD+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
1% of the activity with NAD+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
1% of the activity with NAD+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
in the reverse reaction only 4% of the reaction occurs at neutral pH
-
-
r
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
the enzyme is specific for NADP+ and completely inactive with NAD+
-
-
r
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
about 3times more active with NADP+ than with NAD+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
about 3times more active with NADP+ than with NAD+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
although they can utilize both NAD+ and NADP+: GlcDH-III and GlcDH-IV prefer NAD+, and GlcDH-I and GlcDH-II prefer NADP+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
the enzyme is highly specific for beta-D-glucose
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
GDH-2 is absolutely specific for D-glucose. D-galactose, D-allose, D-mannose, D-xylose, L-arabinose, D-ribose, D-xylose, D-arabinose, L-xylose, D-glucosamine, 2-deoxy-D-glucose, D-fucose, D-lactose, D-maltose, D-fructose and ethanol were not used as substrates. kcat/Km of NADP+ is about 8fold higher compared to kcat/Km of NAD+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
GDH-2 is absolutely specific for D-glucose. D-galactose, D-allose, D-mannose, D-xylose, L-arabinose, D-ribose, D-xylose, D-arabinose, L-xylose, D-glucosamine, 2-deoxy-D-glucose, D-fucose, D-lactose, D-maltose, D-fructose and ethanol were not used as substrates. kcat/Km of glucose in the reaction with NADP+ is about 8fold higher compared to kcat/Km of glucose in reaction with NAD+
-
-
?
beta-D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
100fold higher affinity for NADP+ than for NAD+
-
-
ir
beta-D-glucose 6-phosphate + NADP+
D-glucono-1,5-lactone 6-phosphate + NADPH
-
-
-
-
?
beta-D-glucose 6-phosphate + NADP+
D-glucono-1,5-lactone 6-phosphate + NADPH
-
-
-
-
?
D-galactose + NAD(P)+
D-galactono-1,5-lactone + NAD(P)H
-
low activity with wild-type and mutant enzymes
-
-
?
D-galactose + NAD(P)+
D-galactono-1,5-lactone + NAD(P)H
equally active compared to beta-D-glucose
-
-
?
D-galactose + NAD+
D-galactono-1,5-lactone + NADH
-
15% of the activity with D-glucose and NAD+
-
-
?
D-galactose + NAD+
D-galactono-1,5-lactone + NADH + H+
relative activity: 17.3%
-
-
?
D-galactose + NAD+
D-galactono-1,5-lactone + NADH + H+
relative activity: 17.3%
-
-
?
D-galactose + NAD+
D-galactono-1,5-lactone + NADH + H+
substrate specificity wild-tpye: 2.9% (reference: D-glucose 100%)
-
-
?
D-galactose + NAD+
D-galactono-1,5-lactone + NADH + H+
substrate specificity wild-tpye: 9.1% (reference: D-glucose 100%)
-
-
?
D-galactose + NADP+
D-galactono-1,5-lactone + NADPH
-
5% of the activity with D-glucose
-
-
?
D-galactose + NADP+
D-galactono-1,5-lactone + NADPH
activity with substrate D-galactose in presence of cosubstrate NADP+
-
-
?
D-galactose + NADP+
D-galactono-1,5-lactone + NADPH
activity with substrate D-galactose in presence of cosubstrate NADP+
-
-
?
D-glucosamine + NAD+
D-glucosamino-1,5-lactone + NADH + H+
substrate specificity wild-tpye: 11% (reference: D-glucose 100%)
-
-
?
D-glucosamine + NAD+
D-glucosamino-1,5-lactone + NADH + H+
substrate specificity wild-tpye: 3% (reference: D-glucose 100%)
-
-
?
D-glucose + NAD(P)+
D-glucono-1,5-lactone + NAD(P)H
-
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
the enzyme prefers NAD+ rather than NADP+
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
the enzyme prefers NAD+ rather than NADP+
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
-
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
100% activity
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
-
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
100% activity
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
relative activity: 100%
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
about 20% activity with D-galactose, D-xylose, maltose
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
relative activity: 100%
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
about 20% activity with D-galactose, D-xylose, maltose
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
100% relative activity
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
100% activity
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
Priestia megaterium M1286
-
100% relative activity
-
-
?
D-glucose + NAD+
D-glucono-1,5-lactone + NADH + H+
-
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
the enzyme prefers NAD+ rather than NADP+
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
the enzyme prefers NAD+ rather than NADP+
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
100% activity
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
100% activity
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
-
75% relative activity
-
-
?
D-glucose + NADP+
D-glucono-1,5-lactone + NADPH + H+
Priestia megaterium M1286
-
75% relative activity
-
-
?
D-glucose 6-phosphate + NADP+
D-glucono-1,5-lactone 6-phosphate + NADPH + H+
-
-
-
-
?
D-glucose 6-phosphate + NADP+
D-glucono-1,5-lactone 6-phosphate + NADPH + H+
-
other substrates: hexose-6-phosphates, glucose-6-sulfate, glucose
-
-
?
D-glucose 6-phosphate + NADP+
D-glucono-1,5-lactone 6-phosphate + NADPH + H+
-
-
-
-
?
D-glucose 6-phosphate + NADP+
D-glucono-1,5-lactone 6-phosphate + NADPH + H+
-
-
-
-
?
D-glucose 6-phosphate + NADP+
D-glucono-1,5-lactone 6-phosphate + NADPH + H+
-
-
-
-
?
D-glucose 6-phosphate + NADP+
D-glucono-1,5-lactone 6-phosphate + NADPH + H+
-
-
-
-
?
D-glucose 6-phosphate + NADP+
D-glucono-1,5-lactone 6-phosphate + NADPH + H+
-
-
-
-
?
D-maltose + NAD(P)+
? + NAD(P)H
-
no activity with mutants Q252L and Q252L/E170K
-
-
?
D-maltose + NAD+
?
10% of the activity as compared to D-glucose
-
-
?
D-maltose + NAD+
?
10% of the activity as compared to D-glucose
-
-
?
D-mannose + NAD+
D-mannono-1,5-lactone + NADH
-
2% relative activity
-
-
?
D-mannose + NAD+
D-mannono-1,5-lactone + NADH
Priestia megaterium M1286
-
2% relative activity
-
-
?
D-mannose + NAD+
D-mannono-1,5-lactone + NADH + H+
relative activity: 7.6%
-
-
?
D-mannose + NAD+
D-mannono-1,5-lactone + NADH + H+
substrate specificity wild-tpye: 18% (reference: D-glucose 100%)
-
-
?
D-mannose + NAD+
D-mannono-1,5-lactone + NADH + H+
substrate specificity wild-tpye: 4.8% (reference: D-glucose 100%)
-
-
?
D-mannose + NADP+
D-mannono-1,5-lactone + NADPH
-
88% of the activity with D-glucose
-
-
?
D-mannose + NADP+
D-mannono-1,5-lactone + NADPH
-
no activity
-
-
?
D-xylose + NAD(P)+
D-xylono-1,5-lactone + NAD(P)H + H+
-
wild-type and mutant enzymes
-
-
?
D-xylose + NAD(P)+
D-xylono-1,5-lactone + NAD(P)H + H+
-
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
-
44% of the activity with D-glucose
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
-
47% of the activity with D-glucose
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
Corynebacterium sp. 150-1
-
47% of the activity with D-glucose
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
-
47% of the activity with D-glucose
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
-
44% of the activity with D-glucose
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
relative activity: 22.5%
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
relative activity: 22.5%
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
substrate specificity wild-tpye: 10% (reference: D-glucose 100%)
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
substrate specificity wild-tpye: 35% (reference: D-glucose 100%)
-
-
?
D-xylose + NAD+
D-xylono-1,5-lactone + NADH + H+
-
28% of the activity with D-glucose and NAD+
-
-
?
D-xylose + NADP+
D-xylono-1,5-lactone + NADPH + H+
6.1% of the activity as compared to D-glucose
-
-
?
D-xylose + NADP+
D-xylono-1,5-lactone + NADPH + H+
6.1% of the activity as compared to D-glucose
-
-
?
D-xylose + NADP+
D-xylono-1,5-lactone + NADPH + H+
-
28% of the activity with D-glucose and NAD+
-
-
?
D-xylose + NADP+
D-xylono-1,5-lactone + NADPH + H+
activity with substrate D-galactose in presence of cosubstrate NADP+
-
-
?
D-xylose + NADP+
D-xylono-1,5-lactone + NADPH + H+
activity with substrate D-galactose in presence of cosubstrate NADP+
-
-
?
gentiobiose + NAD+
? + NADH
-
103% of the activity with gentiobiose
-
-
?
maltose + NAD+
? + NADH
-
6% of the activity with D-glucose
-
-
?
maltose + NAD+
? + NADH
Bacillus sp. (in: Bacteria) BG 1722
-
6% of the activity with D-glucose
-
-
?
maltose + NADP+
? + NADPH
-
5% of the activity D-glucose and NAD+
-
-
?
maltose + NADP+
? + NADPH
Bacillus sp. (in: Bacteria) BG 1722
-
5% of the activity D-glucose and NAD+
-
-
?
additional information
?
-
-
no activity with sucrose
-
-
?
additional information
?
-
-
no activity with sucrose
-
-
?
additional information
?
-
Cys residues are not involved in the catalytic site
-
-
?
additional information
?
-
-
no activity of wild-type and mutant enzymes with sucrose
-
-
?
additional information
?
-
-
no activity with D-galactose, D-ribose, D-fructose, and myo-inositol with NAD+ as the cosubstrate
-
-
?
additional information
?
-
-
no activity with N-acetyl-D-glucosamine, D-glucose-6-phosphate, D-arabinose, D-ribose, and myo-inositol
-
-
?
additional information
?
-
no activity with N-acetyl-D-glucosamine, D-glucose-6-phosphate, D-arabinose, D-ribose, and myo-inositol
-
-
?
additional information
?
-
no activity with N-acetyl-D-glucosamine, D-glucose-6-phosphate, D-arabinose, D-ribose, and myo-inositol
-
-
?
additional information
?
-
Priestia megaterium IAM 1030
-
no activity with N-acetyl-D-glucosamine, D-glucose-6-phosphate, D-arabinose, D-ribose, and myo-inositol
-
-
?
additional information
?
-
Priestia megaterium IAM 1030
no activity with N-acetyl-D-glucosamine, D-glucose-6-phosphate, D-arabinose, D-ribose, and myo-inositol
-
-
?
additional information
?
-
Priestia megaterium IWG3
no activity with N-acetyl-D-glucosamine, D-glucose-6-phosphate, D-arabinose, D-ribose, and myo-inositol
-
-
?
additional information
?
-
Priestia megaterium M1286
-
no activity with D-galactose, D-ribose, D-fructose, and myo-inositol with NAD+ as the cosubstrate
-
-
?
additional information
?
-
D-ribose, maltose, lactose and sucrose are poor substrates, no activity with D-allose, D-arabinose, and D-mannose
-
-
?
additional information
?
-
no substrates: D-allose, D-mannose, L-arabinose, D-ribose, D-arabinose, L-xylose, D-glucosamine, 2-deoxy-D-glucose, D-fucose, D-lactose, D-maltose, D-fructose, ethanol
-
-
?
additional information
?
-
no substrates: D-allose, D-mannose, L-arabinose, D-ribose, D-arabinose, L-xylose, D-glucosamine, 2-deoxy-D-glucose, D-fucose, D-lactose, D-maltose, D-fructose, ethanol
-
-
?
additional information
?
-
-
broad substrate specificity, no activity with D-mannose, D-ribose, and glucose 6-phosphate, cofactor specificity depends on the sugar sustrate
-
-
?
additional information
?
-
-
broad substrate specificity, no activity with D-mannose, D-ribose, and glucose 6-phosphate, cofactor specificity depends on the sugar sustrate
-
-
?
