1.1.1.395: 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase

This is an abbreviated version!
For detailed information about 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase, go to the full flat file.

Reaction

Synonyms

3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase, baiA1, baiA2, baiA3, bile acid-inducible 3 alpha-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.395 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase

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Results	in table
77	AA Sequence
3	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
30	kcat/KM [mM/s]
30	KM Value [mM]
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
38	Organism
3	Pathway
2	Protein Variants
2	Purification (Commentary)
1	Reaction
8	Reference
24	Substrates and Products (Substrate)
3	Subunits
20	Synonyms
1	Systematic Name
30	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.1.1.395 - 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

3-oxochenodeoxycholoyl-CoA + NAD+

? + NADH + H+

2 entries

3-oxocholoyl CoA + NAD+

? + NADH + H+

2 entries

3-oxodeoxycholoyl-CoA + NAD+

? + NADH + H+

2 entries

3-oxolithocholoyl-CoA + NAD+

? + NADH + H+

2 entries

3alpha-hydroxy bile acid CoA ester + NAD+

3-oxo bile acid CoA ester + NADH + H+

2 entries

chenodeoxycholic acid + NAD+

7-alpha-hydroxy-3-oxo-5beta-cholanate + NADH + H+

2 entries

chenodeoxycholoyl-CoA + NADP+

3-oxochenodeoxycholoyl-CoA + NADPH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

chenodeoxycholyl CoA + NAD+

3-oxo-chenodeoxycholy-CoA + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

cholic acid + NAD+

3-oxocholic acid + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

cholic acid + NAD+

? + NADH + H+

Eubacterium sp.

-

-

347986

-

-

?

choloyl-CoA + NAD+

3-oxocholoyl-CoA + NADH + H+

2 entries

deoxycholoyl-CoA + NAD+

3-oxodeoxycholoyl-CoA + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

glycocholic acid + NAD+

N-[7alpha,12-alpha-3,24-dioxo-5beta-cholan-24-yl]glycine + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

lithocholoyl-CoA + NAD+

3-oxolithocholoyl-CoA + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

taurocholic acid + NAD+

3-oxotaurocholic acid + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

3-oxochenodeoxycholoyl-CoA + NAD+

? + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

3-oxochenodeoxycholoyl-CoA + NAD+

? + NADH + H+

[Clostridium] scindens VPI 12708

P19337

-

739615

-

-

?

3-oxocholoyl CoA + NAD+

? + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

3-oxocholoyl CoA + NAD+

? + NADH + H+

[Clostridium] scindens VPI 12708

P19337

-

739615

-

-

?

3-oxodeoxycholoyl-CoA + NAD+

? + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

3-oxodeoxycholoyl-CoA + NAD+

? + NADH + H+

[Clostridium] scindens VPI 12708

P19337

-

739615

-

-

?

3-oxolithocholoyl-CoA + NAD+

? + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

3-oxolithocholoyl-CoA + NAD+

? + NADH + H+

[Clostridium] scindens VPI 12708

P19337

-

739615

-

-

?

3alpha-hydroxy bile acid CoA ester + NAD+

3-oxo bile acid CoA ester + NADH + H+

Eubacterium sp.

-

-

738494, 739040

-

-

?

3alpha-hydroxy bile acid CoA ester + NAD+

3-oxo bile acid CoA ester + NADH + H+

Eubacterium sp. VPI 12708

-

-

738494, 739040

-

-

?

chenodeoxycholic acid + NAD+

7-alpha-hydroxy-3-oxo-5beta-cholanate + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?

chenodeoxycholic acid + NAD+

7-alpha-hydroxy-3-oxo-5beta-cholanate + NADH + H+

[Clostridium] scindens VPI 12708

P19337

-

739615

-

-

?

choloyl-CoA + NAD+

3-oxocholoyl-CoA + NADH + H+

Eubacterium sp.

-

preferred substrate

347986

-

-

?

choloyl-CoA + NAD+

3-oxocholoyl-CoA + NADH + H+

[Clostridium] scindens

P19337

-

739615

-

-

?