1.1.1.383: ketol-acid reductoisomerase [NAD(P)+]
This is an abbreviated version!
For detailed information about ketol-acid reductoisomerase [NAD(P)+], go to the full flat file.
Reaction
Synonyms
ilvC, Shewana3_0355
ECTree
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KM Value
KM Value on EC 1.1.1.383 - ketol-acid reductoisomerase [NAD(P)+]
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0.015
mutant V48L/R49P/K52L/S53D/E59K/T182S/E320K, pH not specified in the publication, temperature not specified in the publication
0.024
NADH
-
pH 7, temperature not specified in the publication, cosubstrate: (2S)-2-hydroxy-2-methyl-3-oxobutanoate
0.026
NADH
mutant A71S/R76D/S78D/Q110V/D146G/G185R/K433E , pH not specified in the publication, temperature not specified in the publication
0.03
NADH
mutant A71S/R76D/S78D/Q110V, pH 7.0, temperature not specified in the publication
0.03
NADH
mutant A71S/R76D/S78D/Q110V, pH not specified in the publication, temperature not specified in the publication
0.039
NADH
-
pH 7, temperature not specified in the publication, cosubstrate: (2S)-2-hydroxy-2-methyl-3-oxobutanoate
0.04
NADH
mutant A71S/R76D/S78D/Q110A, pH 7.0, temperature not specified in the publication
0.045
NADH
wild-type, pH not specified in the publication, temperature not specified in the publication
0.047
NADH
mutant S61D/S63D/I95V, pH not specified in the publication, temperature not specified in the publication
0.065
NADH
mutant S78D/Q110V, pH 7.0, temperature not specified in the publication
0.075
NADH
mutant A71S/R76D/S78AD/Q110V, pH not specified in the publication, temperature not specified in the publication
0.09
NADH
mutant R76D/Ser78D, pH not specified in the publication, temperature not specified in the publication
0.108
NADH
mutant V48L/R49P/K52L/S53D, pH not specified in the publication, temperature not specified in the publication
0.113
NADH
mutant S61D/S63D, pH not specified in the publication, temperature not specified in the publication
0.128
NADH
mutant V48L/R49P/K52E/S53D, pH not specified in the publication, temperature not specified in the publication
0.13
NADH
mutant S78D, pH 7.0, temperature not specified in the publication
0.14
NADH
mutant Q110V, pH 7.0, temperature not specified in the publication
0.28
NADH
mutant Q110A, pH 7.0, temperature not specified in the publication
0.285
NADH
wild-type, pH not specified in the publication, temperature not specified in the publication
0.415
NADH
wild-type, pH not specified in the publication, temperature not specified in the publication
1.075
NADH
wild-type, pH not specified in the publication, temperature not specified in the publication
1.08
NADH
wild-type, pH 7.0, temperature not specified in the publication
0.001
wild-type, pH not specified in the publication, temperature not specified in the publication
0.001
NADPH
wild-type, pH not specified in the publication, temperature not specified in the publication
0.013
NADPH
wild-type, pH not specified in the publication, temperature not specified in the publication
0.013
NADPH
mutant Q110V, pH 7.0, temperature not specified in the publication
0.024
NADPH
mutant Q110A, pH 7.0, temperature not specified in the publication
0.031
NADPH
-
pH 7, temperature not specified in the publication, cosubstrate: (2S)-2-hydroxy-2-methyl-3-oxobutanoate
0.04
NADPH
wild-type, pH 7.0, temperature not specified in the publication
0.041
NADPH
wild-type, pH not specified in the publication, temperature not specified in the publication
0.046
NADPH
-
pH 7, temperature not specified in the publication, cosubstrate: (2S)-2-hydroxy-2-methyl-3-oxobutanoate
0.065
NADPH
mutant S78D/Q110V, pH 7.0, temperature not specified in the publication
0.57
NADPH
mutant A71S/R76D/S78D/Q110A, pH 7.0, temperature not specified in the publication
0.6
NADPH
mutant A71S/R76D/S78AD/Q110V, pH not specified in the publication, temperature not specified in the publication
0.65
NADPH
mutant A71S/R76D/S78D/Q110V, pH 7.0, temperature not specified in the publication
0.65
NADPH
mutant A71S/R76D/S78D/Q110V, pH not specified in the publication, temperature not specified in the publication
0.66
NADPH
mutant S78D, pH 7.0, temperature not specified in the publication
0.75
NADPH
mutant V48L/R49P/K52L/S53D/E59K/T182S/E320K, pH not specified in the publication, temperature not specified in the publication
0.88
NADPH
mutant S61D/S63D, pH not specified in the publication, temperature not specified in the publication
1
NADPH
mutant R76D/Ser78D, pH not specified in the publication, temperature not specified in the publication
1
NADPH
mutant S61D/S63D/I95V, pH not specified in the publication, temperature not specified in the publication
1
NADPH
mutant V48L/R49P/K52L/S53D, pH not specified in the publication, temperature not specified in the publication
1.18
NADPH
mutant V48L/R49P/K52E/S53D, pH not specified in the publication, temperature not specified in the publication
1.4
NADPH
mutant A71S/R76D/S78D/Q110V/D146G/G185R/K433E , pH not specified in the publication, temperature not specified in the publication
additional information
-
Km-value for NADH is below 0.001 mM, pH 7, temperature not specified in the publication, cosubstrate: (2S)-2-hydroxy-2-methyl-3-oxobutanoate
additional information
NADPH
-
Km-value for NADPH is below 0.001 mM, pH 7, temperature not specified in the publication, cosubstrate: (2S)-2-hydroxy-2-methyl-3-oxobutanoate