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1.1.1.37: malate dehydrogenase

This is an abbreviated version!
For detailed information about malate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.37

Reaction

(S)-malate
+
NAD+
=
oxaloacetate
 +
NADH
 +
H+

Synonyms

(R)-2-hydroxyacid dehydrogenase, (S)-malate dehydrogenase, A8B73_11505, CaMDH, cMDH, cMDH -S, cMDH-L, cyMDH, cyMDH1, cyMDH2, cyMDH3, cytMDH, cytMDH1, cytosolic malate dehydrogenase, cytosolic malate dehydrogenase 1, cytosolic MDH, cytosolic NAD-dependent malate dehydrogenase, flo16, floury endosperm16, halophilic malate dehydrogenase, HmMalDH, L-malate dehydrogenase, L-malate dehydrogenases, L-malate-NAD oxidoreductase, L-malate-NAD-oxidoreductase, L-malate: NAD oxidoreductase, L-malate: NAD+ oxidoreductase, L-malate:NAD oxidoreductase, L-malate:NAD-oxidoreductase, L-MDH, LDH-like malate dehydrogenase, ldh0076, LEUM_0076, m-MDH, malate (NAD) dehydrogenase, malate dehydrogenase, malate dehydrogenase (NAD), malate dehydrogenase 1, malate dehydrogenase 2, malate: NAD oxidoreductase, MalDH, malic acid dehydrogenase, malic dehydrogenase, mbNAD-MDH, MDH, MDH A, MDH B1, MDH B2, Mdh1, MDH2, Mdh2a, Mdh2b, Mdh3, mitochondrial malate dehydrogenase, mitochondrial MDH, mMDH, mNAD-MDH, More, NAD+ malate dehydrogenase, NAD+-dependent malate dehydrogenase, NAD+-dependent MDH, NAD+-MDH enzymes, NAD-dependent cytosolic malate dehydrogenase, NAD-dependent malate dehydrogenase, NAD-dependent MalDH, NAD-dependent malic dehydrogenase, NAD-dependent MDH, NAD-L-malate dehydrogenase, NAD-linked malate dehydrogenase, NAD-malate dehydrogenase, NAD-malic dehydrogenase, NAD-MDH, NAD-specific malate dehydrogenase, NADP+-dependent malate dehydrogenase, Pcal_1699, pdNAD-MDH, peroxisomal malate dehydrogenase, peroxisomal NAD+-malate dehydrogenase 1, peroxisomal NAD+-malate dehydrogenase 2, plastid-localized NAD-dependent MDH, plastidial NAD+-dependent malate dehydrogenase, plastidial NAD-dependent malate dehydrogenase, plastidial NAD-dependent malate dehydrogenase 1, plNAD-MDH, PMDH, PMDH1, PMDH2, regulatory subunit of nucleic acid-conducting channel, s-MDH, SrMalDH, TaMDH, VEG69, Vegetative protein 69, YlMdh2p, [LDH-like] MDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.37 malate dehydrogenase

pH Optimum

pH Optimum on EC 1.1.1.37 - malate dehydrogenase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10.4
-
malate oxidation
4.3 - 7
-
reduction of ketomalonate
5.5 - 8.5
-
reduction of oxaloacetate, cytosolioc enzyme
6.5 - 7.3
-
conversion of oxaloacetate to L-malate
6.6 - 7
-
oxaloacetate reduction
6.7
-
reduction of oxaloacetate
6.7 - 7.5
Coccochloris peniocystis
-
-
6.8
50°C, phosphate buffer, recombinant enzyme, reduction and oxidation
6.8 - 7
-
-
7 - 8.2
-
reduiction of oxaloacetate, enzyme from ischemic rats
7.2 - 7.8
-
reduction of oxaloacetate, enzyme from normal rats
7.2 - 8.4
-
oxidation of malate
7.5 - 8
7.5 - 8.3
-
Tv 10-02, reduction of oxaloacetate
7.5 - 8.5
-
oxaloacetate reduction
7.5 - 9.5
7.6 - 8.2
in both 50 mM Tricine-KOH and 50 mM potassium phosphate buffer
7.7
-
reduction of oxaloacetate
7.75 - 8.5
-
reduction of oxaloacetate
7.8 - 7.9
-
Tv-1961, reduction of oxaloacetate
7.9
assay at, malate oxidation reaction
8 - 8.5
-
conversion of oxaloacetate to L-malate
8.2 - 8.6
-
conversion of L-malate to oxaloacetate
8.2 - 9.4
-
reduction of oxaloacetate with NADH
8.5 - 9.5
-
malate oxidation
8.6 - 9
-
conversion of L-malate to oxaloacetate
8.9
-
reduction of oxaloacetate, dimeric enzyme form
9.2 - 10.7
-
malate oxidation, strain Tv-1961
9.2 - 9.6
-
reduction of oxalacetate to malate
9.3 - 9.5
-
both isoenzymes
9.5 - 10
9.7
-
oxidation of malate, tetrameric enzyme form