Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.1.363: glucose-6-phosphate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about glucose-6-phosphate dehydrogenase [NAD(P)+], go to the full flat file.

Word Map on EC 1.1.1.363

Reaction

D-glucose 6-phosphate
+
NAD(P)+
=
6-phospho-D-glucono-1,5-lactone
 +
NAD(P)H
 +
H+

Synonyms

G6-PDH, G6PD, G6PDH, G6PDH-1, Glc6PD, Glu-6-PDH, glucose 6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase Zwf, NADP+- and NAD+-dependent G6PDH, PputG6PDH-1, zwf-1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.363 glucose-6-phosphate dehydrogenase [NAD(P)+]

Reference

topprint

Reference on EC 1.1.1.363 - glucose-6-phosphate dehydrogenase [NAD(P)+]

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Naylor, C.E., Gover, S.; Basak, A.K.; Cosgrove, M.S.; Levy, H.R.; Adams, M.J.
NADP+ and NAD+ binding to the dual coenzyme specific enzyme Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: different interdomain hinge angles are seen in different binary and ternary complexes
Acta Crystallogr. Sect. D
57
635-648
2001
Leuconostoc mesenteroides (P11411)
Manually annotated by BRENDA team
Grove, T.H.; Ishaque, A.; Levy, H.R.
Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides. Interaction of the enzyme with coenzymes and coenzyme analogs
Arch. Biochem. Biophys.
17
307-316
1976
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Levy, H.R.; Daouk, G.H.; Katopes, M.A.
Regulation of coenzyme utilization by the dual nucleotide-specific glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroids
Arch. Biochem. Biophys.
198
406-413
1979
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Levy, H.R.; Christoff, M.; Ingulli, J.; Ho, E.M.
Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides: revised kinetic mechanism and kinetics of ATP inhibition
Arch. Biochem. Biophys.
222
473-488
1983
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Kurlandsky, S.B.; Hilburger, A.C.; Levy, H.R.
Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides: ligand-induced conformational changes
Arch. Biochem. Biophys.
264
93-102
1988
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Szweda, L.I.; Stadtman, E.R.
Oxidative modification of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides by an iron(II)-citrate complex
Arch. Biochem. Biophys.
301
391-395
1993
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Levy, H.R.; Vought, V.E.; Yin, X.; Adams, M.J.
Identification of an arginine residue in the dual coenzyme-specific glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides that plays a key role in binding NADP+ but not NAD+
Arch. Biochem. Biophys.
326
145-151
1996
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Coe, E.L.; Hsu, L.H.
Acyl coenzyme A inhibition of Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase: a comparison of the TPN and DPN linked reactions
Biochem. Biophys. Res. Commun.
53
66-69
1973
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Haghighi, B.; Levy, H.R.
Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides. Conformational transitions induced by nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide phosphate, and glucose 6-phosphate monitored by fluorescent probes
Biochemistry
21
6421-6428
1982
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Haghighi, B.; Levy, H.R.
Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides. Kinetics of reassociation and reactivation from inactive subunits
Biochemistry
21
6429-6434
1982
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Crans, D.C., Schelble, S.M.
Vanadate dimer and tetramer both inhibit glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides
Biochemistry
29
6698-6706
1990
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Cosgrove, M.S.; Naylor, C.; Paludan, S.; Adams, M.J.; Levy, H.R.
On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase
Biochemistry
37
2759-2767
1998
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Cosgrove, M.S.; Gover, S.; Naylor, C.E.; Vandeputte-Rutten, L.; Adams, M.J.; Levy, H.R.
An examination of the role of asp-177 in the His-Asp catalytic dyad of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: X-ray structure and pH dependence of kinetic parameters of the D177N mutant enzyme
Biochemistry
39
15002-15011
2000
Leuconostoc mesenteroides (P11411)
Manually annotated by BRENDA team
Vought, V.; Ciccone, T.; Davino, M.H.; Fairbairn, L.; Lin, Y.; Cosgrove, M.S.; Adams, M.J.; Levy, H.R.
Delineation of the roles of amino acids involved in the catalytic functions of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase
Biochemistry
39
15012-15021
2000
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Plomer, J.J.; Gafni, A.
Denaturation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides by guanidine hydrochloride; identification of inactive, partially unfolded, dimeric intermediates
Biochim. Biophys. Acta
1122
234-242
1992
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Plomer, J.J.; Gafni, A.
Renaturation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides after denaturation in 4 M guanidine hydrochloride: kinetics of aggregation and reactivation
Biochim. Biophys. Acta
1163
89-96
1993
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Murphy, N.B.; McConnell, D.J.; Schwarz, T.F.
Expression of the gene for NAD-dependent glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides cloned in Escherichia coli K-12
J. Bacteriol.
169
334-339
1987
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Olive, C.; Geroch, M.E.; Levy, H.R.
Glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides. Kinetic studies
J. Biol. Chem.
246
2047-2057
1971
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Levy, H.R.; Daouk, G.H.
Simultaneous analysis of NAD- and NADP-linked activities of dual nucleotide-specific dehydrogenases. Application to Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase
J. Biol. Chem.
254
4843-4837
1997
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Adams, M.J.; Levy, H.R.; Moffat, K.
Crystallization and preliminary x-ray data for glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides
J. Biol. Chem.
258
5867-5868
1983
Leuconostoc mesenteroides
Manually annotated by BRENDA team
White, B.J.; Levy, H.R.
Modification of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides with the 2',3'-dialdehyde derivative of NADP+ (oNADP+)
J. Biol. Chem.
262
1223-1229
1987
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Lee, W.T.; Flynn, T.G.; Lyons, C.; Levy, H.R.
Cloning of the gene and amino acid sequence for glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides
J. Biol. Chem.
266
13028-13034
1991
Leuconostoc mesenteroides (P11411), Leuconostoc mesenteroides
Manually annotated by BRENDA team
LaDine, J.R.; Carlow, D.; Lee, W.T.; Cross, R.L.; Flynn, T.G.; Levy, H.R.
Interaction of Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase with pyridoxal 5'-diphospho-5'-adenosine. Affinity labeling of Lys-21 and Lys-343
J. Biol. Chem.
266
5558-5562
1991
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Szweda, L.I.; Stadtman, E.R.
Iron-catalyzed oxidative modification of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides. Structural and functional changes
J. Biol. Chem.
267
3096-3100
1992
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Szweda, L.I.; Uchida, K.; Tsai, L.; Stadtman, E.R.
Inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Selective modification of an active-site lysine
J. Biol. Chem.
268
3342-3347
1993
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Simons, J.R.; Mosisch, M.; Torda, A.E.; Hilterhaus, L.
Site directed immobilization of glucose-6-phosphate dehydrogenase via thiol-disulfide interchange: influence on catalytic activity of cysteines introduced at different positions
J. Biotechnol.
167
1-7
2013
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Ravera, S.; Calzia, D.; Morelli, A.; Panfoli, I.
Oligomerization studies of Leuconostoc mesenteroides G6PD activity after SDS-PAGE and blotting
Mol. Biol.
44
472-476
2010
Leuconostoc mesenteroides
Manually annotated by BRENDA team
Lee, W.T.; Levy, H.R.
Lysine-21 of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase participates in substrate binding through charge-charge interaction
Protein Sci.
1
329-334
1992
Leuconostoc mesenteroides (P11411)
Manually annotated by BRENDA team
Adams, M.J.; Basak, A.K.; Gover, S.; Rowland, P.; Levy, H.R.
Site-directed mutagenesis to facilitate X-ray structural studies of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase
Protein Sci.
2
859-662
1993
Leuconostoc mesenteroides (P11411)
Manually annotated by BRENDA team
Yamashiro, T.; Murata, K.; Kawai, S.
Extremely high intracellular concentration of glucose-6-phosphate and NAD(H) in Deinococcus radiodurans
Extremophiles
21
399-407
2017
Deinococcus radiodurans, Deinococcus radiodurans MK5205
Manually annotated by BRENDA team
Olavarria, K.; Marone, M.P.; da Costa Oliveira, H.; Roncallo, J.C.; da Costa Vasconcelos, F.N.; da Silva, L.F.; Gomez, J.G.
Quantifying NAD(P)H production in the upper Entner-Doudoroff pathway from Pseudomonas putida KT2440
FEBS Open Bio
5
908-915
2015
Pseudomonas putida, Pseudomonas putida KT 2240
Manually annotated by BRENDA team
Cumana, S.; Simons, J.; Liese, A.; Hilterhaus, L.; Smirnova, I.
Immobilization of glucose 6-phosphate dehydrogenase in silica-based hydrogels: A comparative study
J. Mol. Catal. B
85-86
220-228
2013
Leuconostoc mesenteroides
-
Manually annotated by BRENDA team
Olavarria, K.; Marone, M.P.; da Costa Oliveira, H.; Roncallo, J.C.; da Costa Vasconcelos, F.N.; da Silva, L.F.; Gomez, J.G.
Quantifying NAD(P)H production in the upper Entner-Doudoroff pathway from Pseudomonas putida KT2440
FEBS open bio
5
908-915
2015
Pseudomonas putida (A0A1B2F298), Pseudomonas putida KT 2240 (A0A1B2F298)
Manually annotated by BRENDA team
Zhu, S.; Cai, D.; Liu, Z.; Zhang, B.; Li, J.; Chen, S.; Ma, X.
Enhancement of bacitracin production by NADPH generation via overexpressing glucose-6-phosphate dehydrogenase Zwf in Bacillus licheniformis
Appl. Biochem. Biotechnol.
187
1502-1514
2019
Bacillus licheniformis, Bacillus licheniformis DW2
Manually annotated by BRENDA team
Benitez-Rangel, E.; Rodriguez-Hernandez, A.; Velasco-Garcia, R.
The substrate of the glucose-6-phosphate dehydrogenase of Pseudomonas aeruginosa provides structural stability
Biochim. Biophys. Acta Proteins Proteom.
1868
140331
2020
Pseudomonas aeruginosa
Manually annotated by BRENDA team
TranNgoc, K.; Pham, N.; Lee, C.; Jang, S.H.
Cloning, expression, and characterization of a psychrophilic glucose 6-phosphate dehydrogenase from Sphingomonas sp. PAMC 26621
Int. J. Mol. Sci.
20
1362
2019
Sphingomonas sp. PAMC 26621
Manually annotated by BRENDA team
Acero-Navarro, K.E.; Jimenez-Ramirez, M.; Villalobos, M.A.; Vargas-Martinez, R.; Perales-Vela, H.V.; Velasco-Garcia, R.
Cloning, overexpression, and purification of glucose-6-phosphate dehydrogenase of Pseudomonas aeruginosa
Protein Expr. Purif.
142
53-61
2018
Pseudomonas aeruginosa (O68282), Pseudomonas aeruginosa, Pseudomonas aeruginosa ATCC 15692 (O68282)
Manually annotated by BRENDA team