1.1.1.362: aklaviketone reductase
This is an abbreviated version!
For detailed information about aklaviketone reductase, go to the full flat file.
Reaction
Synonyms
DauE
ECTree
1.1.1.362 aklaviketone reductaseAdvanced search results
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Substrates Products on EC 1.1.1.362 - aklaviketone reductase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
aklaviketone + NADPH + H+
aklavinone + NADP+
the enzyme is involved in the biosynthesis of the anthracyclins aclacinomycin and daunomycin. Aklavinone is the last intermediate common to both aclacinomycin and daunomycin biosynthesis
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-
?
aklaviketone + NADPH + H+
aklavinone + NADP+
activity with NADH is 7% of the activity with NADPH
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?
