1.1.1.358: 2-dehydropantolactone reductase

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For detailed information about 2-dehydropantolactone reductase, go to the full flat file.

Reaction

Synonyms

CduCPR, conjugated polyketone reductase, conjugated polyketone reductase C2, CorCPR, CPR, CPR-01, CPR-C1, CPR-C2, ketopantoyl-lactone reductase, NADPH-dependent conjugated polyketone reductase, NADPH-dependent ketopantoyl lactone reductase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.358 2-dehydropantolactone reductase

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Results	in table
5	AA Sequence
8	Application
7	Cloned(Commentary)
8	Cofactor
4	Crystallization (Commentary)
16	General Information
32	Inhibitors
5	kcat/KM [mM/s]
4	Ki Value [mM]
11	KM Value [mM]
1	Metals/Ions
8	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
51	Organism
1	Pathway
3	pH Optimum
2	pH Range
2	pH Stability
1	pI Value
30	Protein Variants
7	Purification (Commentary)
9	Reaction
24	Reference
4	Specific Activity [micromol/min/mg]
44	Substrates and Products (Substrate)
14	Subunits
59	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
5	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 1.1.1.358 - 2-dehydropantolactone reductase

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TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

30

Candida dubliniensis

B9WJQ5

purified recombinant His-tagged enzyme, pH 7.0, 7 h, about 90% activity remaining

761008

40

2 entries

40 - 50

Candida orthopsilosis

-

purified recombinant His6-tagged enzyme, pH 7.0, half-lives of the enzyme at 40, 45 and 50°C are 6.3 h, 3.7 h and 52 min, respectively

761570

50

Candida dubliniensis

B9WJQ5

purified recombinant His-tagged enzyme, pH 7.0, 7 h, about 10% activity remaining

761008

60

Candida parapsilosis

-

pH 7.0, 10 min, 77% loss of activity

347724

40

Candida dubliniensis

B9WJQ5

purified recombinant His-tagged enzyme, pH 7.0, 7 h, about 50% activity remaining

761008

40

Candida parapsilosis

-

pH 7.0, 10 min, 58% loss of activity

347724