1.1.1.355: 2'-dehydrokanamycin reductase
This is an abbreviated version!
For detailed information about 2'-dehydrokanamycin reductase, go to the full flat file.
Reaction
Synonyms
kanK
ECTree
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Substrates Products
Substrates Products on EC 1.1.1.355 - 2'-dehydrokanamycin reductase
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REACTION DIAGRAM
kanamycin A + NADP+
the enzyme is involved in the conversion of kanamycin B to kanamycin A. Kanamycin is a clinically important aminoglycoside antibiotic
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2'-dehydrokanamycin A + NADPH + H+
kanamycin A + NADP+
i.e. (1S,2R,3R,4S,6R)-4,6-diamino-3-(6-amino-6-deoxy-a-D-glucopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside
i.e. (1S,2R,3R,4S,6R)-4,6-diamino-3-[(6-amino-6-deoxy-a-D-arabino-hexopyranosyl-2-ulose)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside
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