1.1.1.351: phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]

This is an abbreviated version!
For detailed information about phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating], go to the full flat file.

Reaction

Synonyms

6-phospho-D-gluconate dehydrogenase (decarboxylating), 6-phospho-D-gluconate:NADP+ 2-oxidoreductase, 6-phosphogluconate dehydrogenase, 6-phosphogluconate dehydrogenase (NADP+/NAD+), 6PGDH, gnd

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.351 phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]

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Results	in table
5	AA Sequence
1	Cloned(Commentary)
8	Cofactor
5	Inhibitors
6	KM Value [mM]
5	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
6	Organism
3	Pathway
2	pH Optimum
1	pH Range
2	pI Value
1	Reaction
5	Reference
4	Source Tissue
4	Specific Activity [micromol/min/mg]
1	Storage Stability
12	Substrates and Products (Substrate)
3	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
1	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 1.1.1.351 - phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]

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60 - 90

Thermotoga maritima

the enzyme has half-life times of 48 and 140 h at 90 and 80°C, respectively. The enzyme retains more than 90% activity for 48 h at 60 and 80°C and retains about 50% enzymatic activity after 48 h at 90°C

700013