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Pawar, S.; Schulz, H.
The structure of the multienzyme complex of fatty acid oxidation from Escherichia coli
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Escherichia coli
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Thieringer, R.; Kunau, W.H.
The beta-oxidation system in catalase-free microbodies of the filamentous fungus Neurospora crassa. Purification of a multifunctional protein possessing 2-enoyl-CoA hydratase, L-3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxyacyl-CoA epimerase activities
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Neurospora crassa
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Fatty acid oxidation complex from Escherichia coli
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Escherichia coli
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Sus scrofa
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Peroxisomal multifunctional enzyme of beta-oxidation metabolizing D-3-hydroxyacyl-CoA esters in rat liver: molecular cloning, expression and characterization
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Rattus norvegicus
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Hillmer, P.; Gottschalk, G.
Solubilization and partial characterization of particulate dehydrogenases from Clostridium kluyveri
Biochim. Biophys. Acta
334
12-23
1974
Clostridium kluyveri
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El-Fakhri, M.; Middleton, B.
The existence of an inner-membrane-bound, long acyl-chain-specific 3-hydroxyacyl-CoA dehydrogenase in mammalian mitochondria
Biochim. Biophys. Acta
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1982
Rattus norvegicus
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Barycki, J.J.; O'Brian, L.K.; Bratt, J.M.; Zhang, R.; Sanishvili, R.; Strauss, A.W.; Banaszak, L.J.
Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism
Biochemistry
38
5786-5789
1999
Homo sapiens
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He, X.Y.; Merz, G.; Mehta, P.; Schulz, H.; Yang, S.Y.
Human brain short chain L-3-hydroxyacyl Coenzyme A dehydrogenase is a singl-domain multifunctional enzyme
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274
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1999
Homo sapiens
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He, X.Y.; Yang, S.Y.
Molecular cloning, expression in Escherichia coli, and characterization of a novel L-3-hydroxyacyl coenzyme A dehydrogenase from pig liver
Biochim. Biophys. Acta
1392
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1998
Sus scrofa
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He, X.Y.; Schulz, H.; Yang, S.Y.
a human brain L-3-hydroxyacyl-coenzyme a dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease
J. Biol. Chem.
273
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1998
Homo sapiens (Q99714), Homo sapiens
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Vredendaal, P.J.C.M.; van den Berg, I.E.T.; Malingre, H.E.M.; Stroobants, A.K.; Olde Weghuis, D.E.M.; Berger, R.
Human short-chain L-3-hydroxyacyl-CoA dehydrogenase: cloning and characterization of the coding sequence
Biochem. Biophys. Res. Commun.
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1996
Homo sapiens (Q16836), Homo sapiens
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Hartmann, D.; Philipp, R.; Schmadel, K.; Birktoft, J.J.; Banaszak, L.J.; Trommer, W.E.
Spatial arrangement of coenzyme and substrates bound to L-3-hydroxyacyl-CoA dehydrogenase as studied by spin-labeled analogues of NAD+ and CoA
Biochemistry
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1991
Sus scrofa
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Birktoft, J.J.; Holden, H.M.; Hamlin, R.; Xuong, N.H.; Banaszak, L.J.
Structure of L-3-hydroxyacyl-coenzyme A dehydrogenase: preliminary chain tracing at 2.8 A resolution
Proc. Natl. Acad. Sci. USA
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1987
Sus scrofa
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Holden, H.M.; Banaszak, L.J.
L-3-hydroxyacyl coenzyme a dehydrogenase
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1983
Sus scrofa
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Holden, H.M.; Banaszak, L.J.; Frieden, C.; McLoughlin, D.J.
Differences in the binding of coenzyme to L-3-hydroxyacyl-Coenzyme A dehydrogenase in the crystalline state and in solution
FEBS Lett.
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1981
Sus scrofa
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Osumi, T.; Hashimoto, T.
Purification and properties of mitochondrial and peroxisomal 3-hydroxyacyl-CoA dehydrogenase from rat liver
Arch. Biochem. Biophys.
203
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1980
Rattus norvegicus
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Shimakata, T.; Fujita, Y.; Kusaka, T.
Purification and characterization of 3-hydroxyacyl-CoA dehydrogenase of Mycobacterium smegmatis
J. Biochem.
86
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1979
Mycolicibacterium smegmatis
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El-Fakhri, M.; Middleton, B.
The existence of two different L-3-hydroxyacyl-coenzymeA dehydrogenases in rat tissues
Biochem. Soc. Trans.
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1979
Rattus norvegicus
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Middleton, B.
3-Oxoacyl-coenzyme A thiolases and L-3-hydroxyacyl-coenzyme A dehydrogenases
Biochem. Soc. Trans.
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1978
Rattus norvegicus
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Bradshaw, R.A.; Noyes, B.E.
L-3-hydroxylacyl coenzyme A dehydrogenase from pig heart muscle
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1975
Sus scrofa
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Noyes, B.E.; Glatthaar, B.E.; Garavelli, J.S.; Bradshaw, R.A.
Structural and functional similarities between mitochondrial malate dehydrogenase and L-3-hydroxyacyl CoA dehydrogenase
Proc. Natl. Acad. Sci. USA
71
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1974
Sus scrofa
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Wininger, M.; Noyes, B.E.; Bradshaw, R.A.; Banaszak, L.J.
L-3-Hydroxacyl coenzyme A dehydrogenase: crystallographic properties of the pig heart enzyme
J. Mol. Biol.
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1974
Sus scrofa
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Noyes, B.E.; Bradshaw, R.A.
L-3-Hydroxyacyl coenzyme A dehydrogenase from pig heart muscle
J. Biol. Chem.
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1973
Sus scrofa
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Noyes, B.E.; Bradshaw, R.A.
L-3-Hydroxyacyl coenzyme A dehydrogenase from pig heart muscle. II. Subunit structure
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1973
Sus scrofa
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Stern, J.R.
Crystalline beta-hydroxybutyryl dehydrogenase from pig heart
Biochim. Biophys. Acta
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1957
Sus scrofa
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Wakil, S.J.; Green, D.E.; Mil, S.; Mahler, H.R.
Studies on the fatty acid oxidizing system of animal tissues. IV. beta-hydroxyacyl coenzyme A dehydrogenase
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1954
Bos taurus
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Winkler, U.; Saftel, W.; Stabenau, H.
A new type of a multifunctional beta-oxidation enzyme in Euglena
Plant Physiol.
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2003
Euglena gracilis, Euglena gracilis 1224-5/25
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Liu, X.; Chu, X.; Yu, W.; Li, P.; Li, D.
Expression and purification of His-tagged rat mitochondrial short-chain 3-hydroxyacyl-CoA dehydrogenase wild-type and Ser137 mutant proteins
Protein Expr. Purif.
37
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2004
Rattus norvegicus
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Puyaubert, J.; Dieryck, W.; Costaglioli, P.; Chevalier, S.; Breton, A.; Lessire, R.
Temporal gene expression of 3-ketoacyl-CoA reductase is different in high and in low erucic acid Brassica napus cultivars during seed development
Biochim. Biophys. Acta
1687
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2005
Brassica napus (Q84X95), Brassica napus (Q84X96), Brassica napus
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van Hove, E.C.; Hansen, T.; Dekker, J.M.; Reiling, E.; Nijpels, G.; Jorgensen, T.; Borch-Johnsen, K.; Hamid, Y.H.; Heine, R.J.; Pedersen, O.; Maassen, J.A.; t Hart, L.M.
The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study
Diabetes
55
3193-3196
2006
Homo sapiens
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He, X.; Yang, S.
Roles of type 10 17beta-hydroxysteroid dehydrogenase in intracrinology and metabolism of isoleucine and fatty acids
Endocr. Metab. Immune Disord. Drug Targets
6
95-102
2006
Homo sapiens
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Yang, S.Y.; He, X.Y.; Schulz, H.
3-Hydroxyacyl-CoA dehydrogenase and short chain 3-hydroxyacyl-CoA dehydrogenase in human health and disease
FEBS J.
272
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2005
Sus scrofa, Homo sapiens (Q16836), Homo sapiens
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Yi, H.; Bojja, R.S.; Fu, J.; Du, L.
Direct evidence for the function of FUM13 in 3-ketoreduction of mycotoxin fumonisins in Fusarium verticillioides
J. Agric. Food Chem.
53
5456-5460
2005
Fusarium verticillioides, Fusarium verticillioides A0149
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Liu, W.; Chen, G.Q.
Production and characterization of medium-chain-length polyhydroxyalkanoate with high 3-hydroxytetradecanoate monomer content by fadB and fadA knockout mutant of Pseudomonas putida KT2442
Appl. Microbiol. Biotechnol.
76
1153-1159
2007
Pseudomonas putida, Pseudomonas putida KT 2442
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Filling, C.; Keller, B.; Hirschberg, D.; Marschall, H.U.; Joernvall, H.; Bennett, M.J.; Oppermann, U.
Role of short-chain hydroxyacyl CoA dehydrogenases in SCHAD deficiency
Biochem. Biophys. Res. Commun.
368
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2008
Homo sapiens
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Liu, X.; Deng, G.; Chu, X.; Li, N.; Wu, L.; Li, D.
Formation of an enolate intermediate is required for the reaction catalyzed by 3-hydroxyacyl-CoA dehydrogenase
Bioorg. Med. Chem. Lett.
17
3187-3190
2007
Rattus norvegicus
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Martens, G.A.; Vervoort, A.; Van de Casteele, M.; Stange, G.; Hellemans, K.; Van Thi, H.V.; Schuit, F.; Pipeleers, D.
Specificity in beta cell expression of L-3-hydroxyacyl-CoA dehydrogenase, short chain, and potential role in down-regulating insulin release
J. Biol. Chem.
282
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2007
Homo sapiens, Rattus norvegicus
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Hiltunen, J.K.
Peroxisomes and beta-oxidation of long-chain unsaturated carboxylic acids
Scand. J. Clin. Lab. Invest. Suppl.
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1991
Rattus norvegicus
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Yang, S.; He, X.
Re: Hadh2 and 3-hydroxyacyl-CoA dehydrogenase
Am. J. Physiol. Endocrinol. Metab.
295
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2008
Mus musculus
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Chung, A.; Liu, Q.; Ouyang, S.P.; Wu, Q.; Chen, G.Q.
Microbial production of 3-hydroxydodecanoic acid by pha operon and fadBA knockout mutant of Pseudomonas putida KT2442 harboring tesB gene
Appl. Microbiol. Biotechnol.
83
513-519
2009
Pseudomonas putida
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Kapoor, R.R.; James, C.; Flanagan, S.E.; Ellard, S.; Eaton, S.; Hussain, K.
3-Hydroxyacyl-coenzyme A dehydrogenase deficiency and hyperinsulinemic hypoglycemia: characterization of a novel mutation and severe dietary protein sensitivity
J. Clin. Endocrinol. Metab.
94
2221-2225
2009
Homo sapiens
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Beaudoin, F.; Wu, X.; Li, F.; Haslam, R.P.; Markham, J.E.; Zheng, H.; Napier, J.A.; Kunst, L.
Functional characterization of the Arabidopsis beta-ketoacyl-coenzyme A reductase candidates of the fatty acid elongase
Plant Physiol.
150
1174-1191
2009
Arabidopsis thaliana
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Taylor, R.C.; Brown, A.K.; Singh, A.; Bhatt, A.; Besra, G.S.
Characterization of a beta-hydroxybutyryl-CoA dehydrogenase from Mycobacterium tuberculosis
Microbiology
156
1975-1982
2010
Mycobacterium tuberculosis (P9WNP7), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (P9WNP7)
brenda
Teufel, R.; Mascaraque, V.; Ismail, W.; Voss, M.; Perera, J.; Eisenreich, W.; Haehnel, W.; Fuchs, G.
Bacterial phenylalanine and phenylacetate catabolic pathway revealed
Proc. Natl. Acad. Sci. USA
107
14390-14395
2010
Escherichia coli, Pseudomonas sp., Pseudomonas sp. Y2
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Schulz, N.; Himmelbauer, H.; Rath, M.; van Weeghel, M.; Houten, S.; Kulik, W.; Suhre, K.; Scherneck, S.; Vogel, H.; Kluge, R.; Wiedmer, P.; Joost, H.G.; Schuermann, A.
Role of medium- and short-chain L-3-hydroxyacyl-CoA dehydrogenase in the regulation of body weight and thermogenesis
Endocrinology
152
4641-4651
2011
Mus musculus
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Narayan, S.B.; Master, S.R.; Sireci, A.N.; Bierl, C.; Stanley, P.E.; Li, C.; Stanley, C.A.; Bennett, M.J.
Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways
PLoS ONE
7
e35048
2012
Mus musculus
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Hawkins, A.B.; Adams, M.W.; Kelly, R.M.
Conversion of 4-hydroxybutyrate to acetyl coenzyme A and its anapleurosis in the Metallosphaera sedula 3-hydroxypropionate/4-hydroxybutyrate carbon fixation pathway
Appl. Environ. Microbiol.
80
2536-2545
2014
Metallosphaera sedula (A4YDS4), Metallosphaera sedula DSM 5348 (A4YDS4)
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Ramos-Vera, W.H.; Weiss, M.; Strittmatter, E.; Kockelkorn, D.; Fuchs, G.
Identification of missing genes and enzymes for autotrophic carbon fixation in crenarchaeota
J. Bacteriol.
193
1201-1211
2011
Metallosphaera sedula (A4YDS4), Metallosphaera sedula DSM 5348 (A4YDS4)
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Schmid, G.; Rene, S.B.; Boll, M.
Enzymes of the benzoyl-coenzyme A degradation pathway in the hyperthermophilic archaeon Ferroglobus placidus
Environ. Microbiol.
17
3289-3300
2015
Ferroglobus placidus (D3RXI4), Ferroglobus placidus DSM 10642 (D3RXI4)
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Xu, Y.; Sun, F.
Purification, crystallization and preliminary crystallographic analysis of 3-hydroxyacyl-CoA dehydrogenase from Caenorhabditis elegans
Acta Crystallogr. Sect. F
69
515-519
2013
Caenorhabditis elegans (P34439), Caenorhabditis elegans
brenda
Kim, E.; Kim, K.
Cloning, expression, purification, crystallization and X-ray crystallographic analysis of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium butyricum
Acta Crystallogr. Sect. F
70
485-488
2014
Clostridium butyricum (C4IEM5), Clostridium butyricum
brenda
Kim, J.; Kim, K.
Cloning, expression, purification, crystallization and X-ray crystallographic analysis of the (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 from Ralstonia eutropha H16
Acta Crystallogr. Sect. F
70
955-958
2014
Cupriavidus necator (Q0KEY8), Cupriavidus necator, Cupriavidus necator ATCC 17699 (Q0KEY8)
brenda
Volodina, E.; Steinbuechel, A.
(S)-3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase (FadB) from fatty acid degradation operon of Ralstonia eutropha H16
AMB Express
4
69
2014
Cupriavidus necator (Q0KEG0), Cupriavidus necator DSM 428 (Q0KEG0)
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Kim, J.; Chang, J.H.; Kim, K.J.
Crystal structure and biochemical properties of the (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 from Ralstonia eutropha
Biochem. Biophys. Res. Commun.
448
163-168
2014
Cupriavidus necator (Q0KEY8), Cupriavidus necator, Cupriavidus necator ATCC 17699 (Q0KEY8)
brenda
Segawa, T.; Nomura, K.H.; Villanueva, S.Y.; Saito, M.; Nomura, K.; Gloriani, N.G.; Yoshida, S.
Identification of leptospiral 3-hydroxyacyl-CoA dehydrogenase released in the urine of infected hamsters
BMC Microbiol.
14
132
2014
Leptospira interrogans serovar Copenhageni (Q72M90), Leptospira interrogans serovar Copenhageni Fiocruz LV4231 (Q72M90)
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Heslegrave, A.; Hussain, K.
Novel insights into fatty acid oxidation, amino acid metabolism, and insulin secretion from studying patients with loss of function mutations in 3-hydroxyacyl-CoA dehydrogenase
J. Clin. Endocrinol. Metab.
98
496-501
2013
Homo sapiens (Q16836), Homo sapiens
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Kim, E.J.; Kim, J.; Ahn, J.W.; Kim, Y.J.; Chang, J.H.; Kim, K.J.
Crystal structure of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium butyricum and its mutations that enhance reaction kinetics
J. Microbiol. Biotechnol.
24
1636-1643
2014
Clostridium butyricum (C4IEM5), Clostridium butyricum
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Xu, Y.; Li, H.; Jin, Y.H.; Fan, J.; Sun, F.
Dimerization interface of 3-hydroxyacyl-CoA dehydrogenase tunes the formation of its catalytic intermediate
PLoS ONE
9
e95965
2014
Caenorhabditis elegans (P34439), Caenorhabditis elegans, Homo sapiens (Q16836), Homo sapiens
brenda
Takenoya, M.; Taguchi, S.; Yajima, S.
Crystal structure and kinetic analyses of a hexameric form of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium acetobutylicum
Acta Crystallogr. Sect. F
74
733-740
2018
Clostridium acetobutylicum
brenda
Toma, C.; Koizumi, N.; Kakita, T.; Yamaguchi, T.; Hermawan, I.; Higa, N.; Yamashiro, T.
Leptospiral 3-hydroxyacyl-CoA dehydrogenase as an early urinary biomarker of leptospirosis
Heliyon
4
e00616
2018
Leptospira interrogans, Leptospira interrogans UP-MMC-NIID
brenda
Segawa, M.; Wen, C.; Orita, I.; Nakamura, S.; Fukui, T.
Two NADH-dependent (S)-3-hydroxyacyl-CoA dehydrogenases from polyhydroxyalkanoate-producing Ralstonia eutropha
J. Biosci. Bioeng.
127
294-300
2019
Cupriavidus necator
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