1.1.1.345: D-2-hydroxyacid dehydrogenase (NAD+)
This is an abbreviated version!
For detailed information about D-2-hydroxyacid dehydrogenase (NAD+), go to the full flat file.
Reaction
+
=
+
+
Synonyms
D-2-HADH, D-2-hydroxyacid dehydrogenase, D-2-hydroxyisocaproate dehydrogenase, D-HicDH, D-isomer specific 2-hydroxyacid dehydrogenase, D-isomer specific NAD+-dependent 2-hydroxyacid dehydrogenase, D-isomer-specific 2-hydroxyacid dehydrogenase, D-lactate dehydrogenase, D-lactate:NAD+ oxidoreductase, D-malate dehydrogenases, D-mandelate dehydrogenase, D-ManDH1, D-ManDH2, D-MDH, D2-HDH, HdhD, Ldb1010, ldh1837, LEUM_1837, ManDH2, NAD-dependent D-2-hydroxyacid dehydrogenase, PanE, R-HicDH
ECTree
pH Optimum
pH Optimum on EC 1.1.1.345 - D-2-hydroxyacid dehydrogenase (NAD+)
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5
-
optimum pH for reaction with pyruvate or 2-oxobutyrate
7.5 - 8.5
-
optimum pH values for reaction with 2-oxoisocaproate
8 - 9
oxidation of (R)-2-hydroxy-4-methylpentanoate
4.5
-
maximal catalytic efficiency, D-mandelate dehydrogenase D-ManDH1
4.5
-
maximal catalytic efficiency, D-mandelate dehydrogenase D-ManDH2
5.5 - 7
reduction of 4-methyl-2-oxopentanoate
5.5 - 7
-
forward reaction
7
-
assay at
7.5
-
assay at