1.1.1.315: 11-cis-retinol dehydrogenase
This is an abbreviated version!
For detailed information about 11-cis-retinol dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.315
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1.1.1.315
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retinal
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retinoids
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11-cis-retinal
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chromophore
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fundus
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photoreceptors
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all-trans-retinol
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albipunctatus
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cralbp
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retinaldehyde-binding
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3alpha-hydroxysteroids
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retinaldehyde
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9-cis-retinol
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androsterone
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photoisomerization
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cis-retinols
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electroretinography
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11-cis-retinaldehyde
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17beta-hydroxysteroid
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17beta
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medicine
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punctata
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interphotoreceptor
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11-cis-retinoids
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retinoid-binding
- 1.1.1.315
- retinal
-
retinoids
- 11-cis-retinal
- chromophore
-
fundus
-
photoreceptors
- all-trans-retinol
-
albipunctatus
-
cralbp
-
retinaldehyde-binding
-
3alpha-hydroxysteroids
- retinaldehyde
- 9-cis-retinol
- androsterone
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photoisomerization
- cis-retinols
-
electroretinography
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11-cis-retinaldehyde
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17beta-hydroxysteroid
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17beta
- medicine
-
punctata
-
interphotoreceptor
-
11-cis-retinoids
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retinoid-binding
Reaction
Synonyms
11-cis RD, 11-cis-RDH, 11-cis-retinol dehydrogenase, 11-cis-Ro-DH, atRDH, cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase, CRAD, CRAD2, cRDH, EC 5.2.1.3, RDH10, RDH5, retinol dehydrogenase 10
ECTree
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Source Tissue
Source Tissue on EC 1.1.1.315 - 11-cis-retinol dehydrogenase
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fetal brain (5% mRNA expression of Rdh5 compared to adult liver), fetal heart (6% mRNA expression of Rdh5 compared to adultliver), fetal kidney (17% mRNA expression of Rdh5 compared to adult liver), fetal liver (20% mRNA expression of Rdh5 compared to adult liver), fetal spleen (5% mRNA expression of Rdh5 compared to adult liver), fetal thymus (7% mRNA expression of Rdh5 compared to adult liver), fetal lung (14% mRNA expression of Rdh5 compared to liver)
additional information
a weak but detectable signal is present in normal lung, the 3 kb isoform is the most abundant one
RDH10 colocalizes with retinal pigment protein RPE65 and with cellular retinaldehyde-binding protein CRALBP in vivo
no expression in H-460 cells (non-small-cell lung cancer). Very low level of expression is detected in cell lines SKMES (squamous lung cancer) and SCLC (small-cell lung carcinoma)
additional information
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mRNA expression is widespread in extra-ocular tissues with human liver and mammary gland showing the most intense signals
additional information
mRNA expression is widespread in extra-ocular tissues with human liver and mammary gland showing the most intense signals