1.1.1.305: UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)
This is an abbreviated version!
For detailed information about UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating), go to the full flat file.
Reaction
Synonyms
ArnA, ArnA dehydrogenase, ArnADH, RsU4kpxs, UDP-alpha-D-xylose synthase, UDP-GlcUA dehydrogenase, UGA decarboxylase, UXS
ECTree
Advanced search results
General Information
General Information on EC 1.1.1.305 - UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
evolution
additional information
-
induced-fit conformational change associated with cofactor binding, overview
-
the ancestral enzyme of UDP-xylose synthase and UDP-apiose/UDP-xylose synthase is diverged to two distinct enzymatic activities in early bacteria. This separation gave rise to the current UDP-xylose synthase in animal, fungus, and plant as well as to the plant Uaxs and bacterial ArnA and U4kpxs homologues
evolution
-
the enzyme is a member of the short-chain dehydrogenase/reductase family of nucleotide-sugar modifying enzymes