1.1.1.298: 3-hydroxypropionate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about 3-hydroxypropionate dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

3-HIBADH, 3-hydroxyisobutyrate dehydrogenase, 3-hydroxypropionate dehydrogenase, bi-functional malonyl-CoA reductase, malonate semialdehyde reductase, malonate semialdehyde reductase (NADPH), malonic semialdehyde reductase, malonyl-CoA reductase, MCR, More, MSAR, Msed_1993

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
2229	AA Sequence
3	Application
1	CAS Registry Number
8	Cloned(Commentary)
24	Cofactor
1	Crystallization (Commentary)
2	Expression
20	General Information
1	General Stability
4	Inhibitors
3	kcat/KM [mM/s]
11	KM Value [mM]
8	Metals/Ions
6	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
42	Organism
10	Pathway
6	pH Optimum
5	pH Range
9	Protein Variants
5	Purification (Commentary)
1	Reaction
20	Reference
3	Source Tissue
7	Specific Activity [micromol/min/mg]
1	Storage Stability
39	Substrates and Products (Substrate)
12	Subunits
40	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
4	Temperature Range [°C]
6	Temperature Stability [°C]
5	Turnover Number [1/s]

Systematic Name

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Systematic Name on EC 1.1.1.298 - 3-hydroxypropionate dehydrogenase (NADP+)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

3-hydroxypropionate:NADP+ oxidoreductase

Catalyses the reduction of malonate semialdehyde to 3-hydroxypropanoate, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutanoate cycles, autotrophic CO2 fixation pathways found in some green non-sulfur phototrophic bacteria and archaea, respectively [1,2]. The enzyme from Chloroflexus aurantiacus is bifunctional, and also catalyses the upstream reaction in the pathway, EC 1.2.1.75 [3]. Different from EC 1.1.1.59 [3-hydroxypropionate dehydrogenase (NAD+)] by cofactor preference.