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1.1.1.281: GDP-4-dehydro-6-deoxy-D-mannose reductase

This is an abbreviated version!
For detailed information about GDP-4-dehydro-6-deoxy-D-mannose reductase, go to the full flat file.

Word Map on EC 1.1.1.281

Reaction

GDP-alpha-D-rhamnose
+
NAD(P)+
=
GDP-4-dehydro-alpha-D-rhamnose
+
NAD(P)H
+
H+

Synonyms

GDP-4-keto-6-deoxy-D-mannose reductase, GDP-4-keto-6-deoxy-D-mannose reductase (ambiguous), GDP-6-deoxy-D-lyxo-4-hexulose reductase, GDP-6-deoxy-D-mannose reductase, RMD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.281 GDP-4-dehydro-6-deoxy-D-mannose reductase

General Information

General Information on EC 1.1.1.281 - GDP-4-dehydro-6-deoxy-D-mannose reductase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
the enzyme consumes the immediate precursor to GDP-L-fucose to produce GDP-D-rhamnose, which might be a dead-end product in recombinant insect cells