1.1.1.272: D-2-hydroxyacid dehydrogenase (NADP+)
This is an abbreviated version!
For detailed information about D-2-hydroxyacid dehydrogenase (NADP+), go to the full flat file.
Word Map on EC 1.1.1.272
-
1.1.1.272
-
dehydrogenases
-
2-hydroxyacids
-
enterococcus
-
nad-dependent
-
d-mandelate
-
2-oxobutyric
-
d-lactate
-
2-ketoisocaproate
-
knowledgebase
-
delbrueckii
-
2-keto
-
4-methylthio
-
benzoylformate
-
haloferax
-
glyoxylate
-
bulgaricus
-
faecium
-
d-2-hydroxyisocaproate
-
mediterranei
- 1.1.1.272
- dehydrogenases
-
2-hydroxyacids
-
enterococcus
-
nad-dependent
- d-mandelate
-
2-oxobutyric
- d-lactate
- 2-ketoisocaproate
-
knowledgebase
- delbrueckii
-
2-keto
-
4-methylthio
- benzoylformate
-
haloferax
- glyoxylate
- bulgaricus
- faecium
-
d-2-hydroxyisocaproate
- mediterranei
Reaction
Synonyms
(R)-2-hydroxyacid dehydrogenase, (R)-sulfolactate dehydrogenase, (R)-sulfolactate:NAD(P)+ oxidoreductase, 2-D-hydroxyacid dehydrogenase, 2-HDH, 2HADH, D-2-hydroxyacid dehydrogenase, D-isomer specific 2-hydroxyacid dehydrogenase, D2-HDH, DDH, DDH_HALMT, HDH, L-2-hydroxyacid dehydrogenase, L-sulfolactate dehydrogenase
ECTree
Advanced search results
Systematic Name
Systematic Name on EC 1.1.1.272 - D-2-hydroxyacid dehydrogenase (NADP+)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
(R)-2-hydroxycarboxylate:NADP+ oxidoreductase
This enzyme, characterized from the halophilic archaeon Haloferax mediterranei and the mold Aspergillus oryzae, catalyses a stereospecific reduction of 2-oxocarboxylic acids into the corresponding D-2-hydroxycarboxylic acids. The enzyme prefers substrates with a main chain of 5 carbons (such as 4-methyl-2-oxopentanoate) to those with a shorter chain, and can use NADH with much lower efficiency. cf. EC 1.1.1.345, (D)-2-hydroxyacid dehydrogenase (NAD+).