1.1.1.270: 3beta-hydroxysteroid 3-dehydrogenase

This is an abbreviated version!
For detailed information about 3beta-hydroxysteroid 3-dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.270

1.1.1.270

steroidogenic

testosterone

androgen

progesterone

steroidogenesis

adrenal

leydig

star

cyp11a1

testicular

p450scc

aromatase

lutein

lh

pregnenolone

androstenedione

dehydroepiandrosterone

akr1c1

granulosa

trilostane

17alpha-hydroxylase

3betahsd

hsd3b2

dheas

dihydrotestosterone

lhcgr

srd5a1

p450arom

5alpha-reductase

21-hydroxylase

3-ketosteroids

scarb1

hsd11b1

22r-hydroxycholesterol

5alpha-dihydrotestosterone

neurosteroids

20alpha-hydroxysteroid

11beta-hydroxylase

cyp21

3alpha-hsds

insl3

intratesticular

lh-stimulated

adrenarche

17-hydroxypregnenolone

medicine

17alpha-hydroxyprogesterone

delta5

pre-receptor

synthesis

analysis

20alpha-hsd

17alpha-hydroxylase/17,20-lyase

Reaction

Synonyms

17beta-HSD7, 17beta-hydroxysteroid dehydrogenase type 7, 3-keto reducing enzyme, 3-keto reductase, 3-keto-reductase, 3-ketoreductase, 3-ketosteroid reductase, 3-KSR, 3-oxo steroid reductase, 3-oxosteroid reductase, 3beta-HSD, 3beta-HSD1, 3beta-HSD2, 3beta-HSDH, 3beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase type 1, 3beta-hydroxysteroid dehydrogenase/Delta 5->4-isomerase type 1, 3beta-hydroxysteroid dehydrogenase/Delta 5->4-isomerase type 2, 3beta-hydroxysteroid dehydrogenase/isomerase, AKR1C1, AKR1C2, AKR1Cs, aldo-keto reductase 1C2, CDD59473, Erg27, Erg27p, Hsd17, HSD17B7, HSD3B1, reductase, 3-oxo steroid, reductive 3beta-HSD, SDR11E1, SDR11E2, steroid-3-ketoreductase, sterol 3-ketoreductase, sterone-reducing enzyme, type 3 3alpha-hydroxysteroid dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase

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Results	in table
4	Activating Compound
363	AA Sequence
3	Application
1	CAS Registry Number
11	Cloned(Commentary)
27	Cofactor
878	Disease/ Diagnostics
1	Expression
22	General Information
4	General Stability
15	IC50 Value
37	Inhibitors
8	kcat/KM [mM/s]
10	Ki Value [mM]
43	KM Value [mM]
19	Localization
1	Metals/Ions
3	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
32	Organism
14	Pathway
8	pH Optimum
19	Protein Variants
5	Purification (Commentary)
4	Reaction
3	Reaction Type
30	Reference
46	Source Tissue
5	Specific Activity [micromol/min/mg]
140	Substrates and Products (Substrate)
1	Subunits
52	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
2	Temperature Stability [°C]
32	Turnover Number [1/s]

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Turnover Number on EC 1.1.1.270 - 3beta-hydroxysteroid 3-dehydrogenase

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0.003 - 0.052

17beta-hydroxy-5alpha-androstan-3-one

3 entries

0.007

3-oxodeoxycholic acid

Eggerthella sp. CAG:298

R7AF73

coenzyme: NADPH, pH 6.5, temperature not specified in the publication

760397

0.02 - 0.113

5beta-dihydrotestosterone

5 entries

0.023 - 0.092

5beta-pregnane-21-ol-3,20-dione

5 entries

0.055 - 0.13

dehydroepiandrosterone

3 entries

0.022

isodeoxycholic acid

Eggerthella sp. CAG:298

R7AF73

coenzyme: NADP+, pH 9.5, temperature not specified in the publication

760397

0.3 - 0.58

methylglyoxal

5 entries

0.04 - 0.1

NAD+

3 entries

0.73

NADPH

Oryctolagus cuniculus

pH 7.4, 25°C, wild-type enzyme

724124

0.6 - 1.2

Pyridine-3-aldehyde

5 entries